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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRP54
All Species:
43.64
Human Site:
S12
Identified Species:
68.57
UniProt:
P61011
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61011
NP_001139754.1
504
55705
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Chimpanzee
Pan troglodytes
XP_001135953
451
49877
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P14576
504
55702
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Rat
Rattus norvegicus
Q6AYB5
504
55686
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421238
504
55678
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Frog
Xenopus laevis
NP_001080564
504
55541
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Zebra Danio
Brachydanio rerio
NP_957282
504
55734
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523931
508
55847
T12
D
L
G
R
K
I
T
T
A
L
H
S
L
S
K
Honey Bee
Apis mellifera
XP_624497
498
55033
S12
D
L
G
R
K
I
T
S
A
L
R
S
L
S
N
Nematode Worm
Caenorhab. elegans
NP_501507
496
54945
N12
D
L
G
R
K
I
R
N
A
I
G
K
L
G
Q
Sea Urchin
Strong. purpuratus
XP_780650
510
55900
S12
D
L
G
R
K
I
T
S
A
L
K
S
L
S
N
Poplar Tree
Populus trichocarpa
XP_002299799
493
54683
R12
Q
L
G
G
S
I
S
R
A
I
Q
Q
M
S
N
Maize
Zea mays
NP_001142208
496
54714
R12
Q
L
G
G
S
I
S
R
A
L
A
Q
M
S
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49967
495
54763
R12
E
L
G
G
R
I
T
R
A
I
Q
Q
M
S
N
Baker's Yeast
Sacchar. cerevisiae
P20424
541
59606
S12
D
L
G
K
R
I
N
S
A
V
N
N
A
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
N.A.
N.A.
N.A.
99.8
99.5
N.A.
N.A.
98.8
95
96
N.A.
76.1
79.7
71
83.3
Protein Similarity:
100
89.4
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
99.8
97.4
98.6
N.A.
89.3
91.2
84.7
91.1
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
80
100
53.3
93.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
100
66.6
100
Percent
Protein Identity:
57.3
57.7
N.A.
56.9
47.3
N.A.
Protein Similarity:
76.9
75.7
N.A.
76.3
66.1
N.A.
P-Site Identity:
40
46.6
N.A.
46.6
40
N.A.
P-Site Similarity:
66.6
60
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
100
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
20
0
0
0
0
0
0
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
100
0
0
0
20
0
0
0
7
0
% I
% Lys:
0
0
0
7
74
0
0
0
0
0
7
7
0
0
7
% K
% Leu:
0
100
0
0
0
0
0
0
0
74
0
0
74
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
7
7
0
0
80
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
0
0
0
0
0
14
20
0
0
7
% Q
% Arg:
0
0
0
74
14
0
7
20
0
0
54
0
0
0
0
% R
% Ser:
0
0
0
0
14
0
14
67
0
0
0
67
0
87
7
% S
% Thr:
0
0
0
0
0
0
74
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _