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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRP54
All Species:
43.03
Human Site:
Y125
Identified Species:
67.62
UniProt:
P61011
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61011
NP_001139754.1
504
55705
Y125
C
S
K
L
A
Y
Y
Y
Q
R
K
G
W
K
T
Chimpanzee
Pan troglodytes
XP_001135953
451
49877
Y125
C
S
K
L
A
Y
Y
Y
Q
R
K
G
W
K
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P14576
504
55702
Y125
C
S
K
L
A
Y
Y
Y
Q
R
K
G
W
K
T
Rat
Rattus norvegicus
Q6AYB5
504
55686
Y125
C
S
K
L
A
Y
F
Y
Q
R
K
G
W
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421238
504
55678
Y125
C
S
K
L
A
Y
F
Y
Q
R
K
G
W
K
T
Frog
Xenopus laevis
NP_001080564
504
55541
Y125
C
T
K
L
A
Y
Y
Y
Q
R
K
G
W
K
T
Zebra Danio
Brachydanio rerio
NP_957282
504
55734
F125
C
S
K
L
A
Y
Y
F
Q
R
K
G
W
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523931
508
55847
Y125
C
T
K
L
A
Y
H
Y
Q
K
R
N
W
K
S
Honey Bee
Apis mellifera
XP_624497
498
55033
Y125
C
T
K
L
A
Y
H
Y
L
K
K
N
W
K
A
Nematode Worm
Caenorhab. elegans
NP_501507
496
54945
Y125
C
T
K
M
A
Y
Y
Y
Q
R
K
G
W
K
T
Sea Urchin
Strong. purpuratus
XP_780650
510
55900
Y125
C
T
K
L
A
Y
Y
Y
Q
K
K
G
W
K
V
Poplar Tree
Populus trichocarpa
XP_002299799
493
54683
H125
C
T
K
Y
A
Y
Y
H
Q
K
K
G
W
K
P
Maize
Zea mays
NP_001142208
496
54714
H125
C
T
K
Y
A
Y
Y
H
Q
K
K
G
F
K
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49967
495
54763
H125
C
T
K
Y
A
Y
Y
H
Q
K
K
G
Y
K
P
Baker's Yeast
Sacchar. cerevisiae
P20424
541
59606
Y133
C
T
K
L
A
V
Y
Y
S
K
R
G
F
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
N.A.
N.A.
N.A.
99.8
99.5
N.A.
N.A.
98.8
95
96
N.A.
76.1
79.7
71
83.3
Protein Similarity:
100
89.4
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
99.8
97.4
98.6
N.A.
89.3
91.2
84.7
91.1
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
60
60
86.6
80
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
80
100
93.3
Percent
Protein Identity:
57.3
57.7
N.A.
56.9
47.3
N.A.
Protein Similarity:
76.9
75.7
N.A.
76.3
66.1
N.A.
P-Site Identity:
66.6
60
N.A.
60
53.3
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
14
7
0
0
0
0
14
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
87
0
0
0
% G
% His:
0
0
0
0
0
0
14
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
100
0
0
0
0
0
0
47
87
0
0
100
0
% K
% Leu:
0
0
0
74
0
0
0
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
87
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
54
14
0
0
0
0
% R
% Ser:
0
40
0
0
0
0
0
0
7
0
0
0
0
0
7
% S
% Thr:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
54
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% W
% Tyr:
0
0
0
20
0
94
74
74
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _