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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB5B All Species: 27.88
Human Site: Y48 Identified Species: 47.18
UniProt: P61020 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61020 NP_002859.1 215 23707 Y48 V K G Q F H E Y Q E S T I G A
Chimpanzee Pan troglodytes XP_001153865 294 32235 Y127 V K G Q F H E Y Q E S T I G A
Rhesus Macaque Macaca mulatta XP_001096821 335 36686 Y176 V K G Q F H E Y Q E S T I G A
Dog Lupus familis XP_856128 222 24457 Y48 V K G Q F H E Y Q E S T I G A
Cat Felis silvestris
Mouse Mus musculus P35278 216 23394 Y49 V K G Q F H E Y Q E S T I G A
Rat Rattus norvegicus Q6GQP4 194 21350 P36 H F D H N I S P T I G A S F M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508982 215 23635 F48 V K G Q F H E F Q E S T I G A
Chicken Gallus gallus Q5ZHW4 215 23596 Y48 V K G Q F H E Y Q E S T I G A
Frog Xenopus laevis NP_001080714 215 23616 Y49 V K G Q F H E Y Q E S T I G A
Zebra Danio Brachydanio rerio NP_958893 216 23476 F49 V K G Q F H E F Q E S T I G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783878 216 23603 Q48 K G Q F H E F Q E S T I G A A
Poplar Tree Populus trichocarpa
Maize Zea mays Q05737 203 22457 F45 I S T I G V D F K I R T V E Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P31582 200 21635 T42 F V E F Q E S T I G A A F F S
Baker's Yeast Sacchar. cerevisiae P36017 210 23062 I51 F L T Q R V T I N E H T V K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.1 60.9 96.8 N.A. 84.2 45.1 N.A. 81.8 96.2 83.2 81 N.A. N.A. N.A. N.A. 83.3
Protein Similarity: 100 73.1 60.9 96.8 N.A. 91.1 63.7 N.A. 91.1 97.6 91.1 90.7 N.A. N.A. N.A. N.A. 89.3
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 93.3 100 100 93.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 100 100 100 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 40.9 N.A. 58.1 53.9 N.A.
Protein Similarity: N.A. 56.7 N.A. 70.2 66.9 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 20 N.A.
P-Site Similarity: N.A. 40 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 15 0 8 72 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 15 65 0 8 72 0 0 0 8 0 % E
% Phe: 15 8 0 15 65 0 8 22 0 0 0 0 8 15 8 % F
% Gly: 0 8 65 0 8 0 0 0 0 8 8 0 8 65 0 % G
% His: 8 0 0 8 8 65 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 0 8 0 8 0 8 8 15 0 8 65 0 0 % I
% Lys: 8 65 0 0 0 0 0 0 8 0 0 0 0 8 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 72 8 0 0 8 65 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 15 0 0 8 65 0 8 0 8 % S
% Thr: 0 0 15 0 0 0 8 8 8 0 8 79 0 0 0 % T
% Val: 65 8 0 0 0 15 0 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _