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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2M All Species: 18.18
Human Site: S28 Identified Species: 28.57
UniProt: P61081 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61081 NP_003960.1 183 20900 S28 K G S S K K A S A A Q L R I Q
Chimpanzee Pan troglodytes XP_001146573 161 18597 S28 L P K T C D I S F S D P D D L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541337 267 28728 S112 K G S S K K A S A A Q L R I Q
Cat Felis silvestris
Mouse Mus musculus Q9CY34 185 21091 R28 A S T S D S T R R V S V R D K
Rat Rattus norvegicus Q5U203 185 21061 R28 A S T S D S T R R V S V R D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKX6 185 21211 R28 N P A S D S T R R V S V R D K
Frog Xenopus laevis Q6DCZ9 183 20935 S28 K G S S K K A S A A Q L R I Q
Zebra Danio Brachydanio rerio Q6NY82 185 21000 H28 A G S N D A A H R V S I R D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSF3 181 20719 Q28 Q K K A S A A Q L R I Q K D I
Honey Bee Apis mellifera XP_392749 181 20511 A28 T Q K K A S A A Q L R I T K D
Nematode Worm Caenorhab. elegans P35129 147 16687 V26 A Q C S A G P V G D D L F H W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313810 183 21014 S28 K S P I K K Q S A G E L R L H
Maize Zea mays NP_001105261 184 20637 S28 K A P V K K Q S A G E L R L H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SDY5 184 20768 S29 G A S V K K Q S A G E L R L H
Baker's Yeast Sacchar. cerevisiae P52491 188 21185 A28 I Q P N L S A A R I R L K R D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 N.A. 68.5 N.A. 40 40 N.A. N.A. 38.9 97.2 37.8 N.A. 75.4 81.4 26.7 N.A.
Protein Similarity: 100 85.7 N.A. 68.5 N.A. 57.2 57.2 N.A. N.A. 57.8 97.8 58.9 N.A. 85.7 89 43.7 N.A.
P-Site Identity: 100 6.6 N.A. 100 N.A. 13.3 13.3 N.A. N.A. 13.3 100 26.6 N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 20 N.A. 100 N.A. 33.3 33.3 N.A. N.A. 33.3 100 46.6 N.A. 26.6 26.6 13.3 N.A.
Percent
Protein Identity: 61.2 64.1 N.A. 60.8 44.6 N.A.
Protein Similarity: 78.6 77.7 N.A. 79.3 63.8 N.A.
P-Site Identity: 46.6 46.6 N.A. 46.6 13.3 N.A.
P-Site Similarity: 60 60 N.A. 60 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 14 7 7 14 14 47 14 40 20 0 0 0 0 0 % A
% Cys: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 27 7 0 0 0 7 14 0 7 40 14 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % F
% Gly: 7 27 0 0 0 7 0 0 7 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 20 % H
% Ile: 7 0 0 7 0 0 7 0 0 7 7 14 0 20 7 % I
% Lys: 34 7 20 7 40 40 0 0 0 0 0 0 14 7 20 % K
% Leu: 7 0 0 0 7 0 0 0 7 7 0 54 0 20 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 14 20 0 0 0 7 0 0 0 0 7 0 0 0 % P
% Gln: 7 20 0 0 0 0 20 7 7 0 20 7 0 0 20 % Q
% Arg: 0 0 0 0 0 0 0 20 34 7 14 0 67 7 7 % R
% Ser: 0 20 34 47 7 34 0 47 0 7 27 0 0 0 0 % S
% Thr: 7 0 14 7 0 0 20 0 0 0 0 0 7 0 0 % T
% Val: 0 0 0 14 0 0 0 7 0 27 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _