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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2M
All Species:
28.35
Human Site:
Y177
Identified Species:
44.56
UniProt:
P61081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61081
NP_003960.1
183
20900
Y177
G
G
Y
I
G
S
T
Y
F
E
R
C
L
K
_
Chimpanzee
Pan troglodytes
XP_001146573
161
18597
Y155
G
G
Y
I
G
S
T
Y
F
E
R
C
L
K
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541337
267
28728
Y261
G
G
Y
I
G
S
T
Y
F
E
R
C
L
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY34
185
21091
Y179
F
R
D
K
V
D
E
Y
I
K
R
Y
A
R
_
Rat
Rattus norvegicus
Q5U203
185
21061
Y179
F
R
D
K
V
D
E
Y
I
K
R
Y
A
R
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKX6
185
21211
Y179
F
R
N
K
V
E
D
Y
I
K
R
Y
A
R
_
Frog
Xenopus laevis
Q6DCZ9
183
20935
Y177
G
G
Y
I
G
S
T
Y
F
E
R
C
L
K
_
Zebra Danio
Brachydanio rerio
Q6NY82
185
21000
F179
F
R
N
K
V
Q
D
F
I
K
N
Y
A
R
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSF3
181
20719
Y174
G
G
C
V
G
E
T
Y
F
E
C
C
L
L
K
Honey Bee
Apis mellifera
XP_392749
181
20511
Y175
G
G
Y
V
G
A
F
Y
F
E
R
C
L
K
_
Nematode Worm
Caenorhab. elegans
P35129
147
16687
W141
Y
N
Q
L
A
R
E
W
T
Q
K
Y
A
M
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313810
183
21014
Maize
Zea mays
NP_001105261
184
20637
Y178
G
G
Y
V
G
Q
H
Y
F
Q
R
C
L
A
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDY5
184
20768
Baker's Yeast
Sacchar. cerevisiae
P52491
188
21185
K181
G
G
S
I
E
H
V
K
Y
D
N
I
V
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
N.A.
68.5
N.A.
40
40
N.A.
N.A.
38.9
97.2
37.8
N.A.
75.4
81.4
26.7
N.A.
Protein Similarity:
100
85.7
N.A.
68.5
N.A.
57.2
57.2
N.A.
N.A.
57.8
97.8
58.9
N.A.
85.7
89
43.7
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
14.2
14.2
N.A.
N.A.
14.2
100
0
N.A.
60
78.5
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
28.5
28.5
N.A.
N.A.
28.5
100
21.4
N.A.
66.6
92.8
28.5
N.A.
Percent
Protein Identity:
61.2
64.1
N.A.
60.8
44.6
N.A.
Protein Similarity:
78.6
77.7
N.A.
79.3
63.8
N.A.
P-Site Identity:
0
64.2
N.A.
0
20
N.A.
P-Site Similarity:
0
78.5
N.A.
0
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
34
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
7
47
0
0
0
% C
% Asp:
0
0
14
0
0
14
14
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
14
20
0
0
40
0
0
0
0
0
% E
% Phe:
27
0
0
0
0
0
7
7
47
0
0
0
0
0
0
% F
% Gly:
54
54
0
0
47
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
34
0
0
0
0
27
0
0
7
0
0
0
% I
% Lys:
0
0
0
27
0
0
0
7
0
27
7
0
0
34
7
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
0
0
47
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
14
0
0
0
0
0
0
0
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
7
0
0
14
0
0
0
14
0
0
0
0
0
% Q
% Arg:
0
27
0
0
0
7
0
0
0
0
60
0
0
27
0
% R
% Ser:
0
0
7
0
0
27
0
0
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
34
0
7
0
0
0
0
0
0
% T
% Val:
0
0
0
20
27
0
7
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
40
0
0
0
0
67
7
0
0
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
74
% _