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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2K
All Species:
9.09
Human Site:
S159
Identified Species:
16.67
UniProt:
P61086
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61086
NP_001104583.1
200
22407
S159
Y
A
G
A
P
V
S
S
P
E
Y
T
K
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P61079
147
16669
P113
I
C
S
L
L
C
D
P
N
P
D
D
P
L
V
Rat
Rattus norvegicus
Q9EQX9
152
17105
D118
L
L
S
A
P
N
P
D
D
P
L
A
N
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512618
165
18346
I131
S
P
E
Y
T
K
K
I
E
N
L
C
A
M
G
Chicken
Gallus gallus
NP_001026711
200
22416
S159
Y
A
G
A
P
V
S
S
P
E
Y
T
R
K
I
Frog
Xenopus laevis
Q7ZY08
192
21535
G157
H
A
L
P
A
P
Q
G
S
D
K
E
S
Q
E
Zebra Danio
Brachydanio rerio
NP_001008611
200
22376
S159
Y
A
G
A
P
V
S
S
P
E
Y
T
R
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52486
199
22491
F159
Y
A
G
G
P
H
T
F
P
D
C
D
S
K
I
Honey Bee
Apis mellifera
XP_001120470
199
22483
M159
Y
A
G
G
P
A
K
M
P
D
L
D
D
K
I
Nematode Worm
Caenorhab. elegans
P52484
229
26047
V188
F
A
N
S
K
K
D
V
E
P
D
F
N
R
K
Sea Urchin
Strong. purpuratus
XP_790028
199
22415
N159
Y
A
G
G
N
T
K
N
Q
E
L
E
Q
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FI61
192
21236
E155
F
A
K
K
S
S
L
E
E
K
V
K
R
L
V
Baker's Yeast
Sacchar. cerevisiae
P21734
215
24160
G155
Y
A
S
E
T
S
N
G
Q
K
G
N
V
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
32.5
37
N.A.
76.5
99.5
36
97
N.A.
68
73.5
41
63
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
50.5
53.5
N.A.
77.5
100
55.5
99.5
N.A.
81.5
84.5
58
78.5
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
0
13.3
N.A.
0
93.3
6.6
93.3
N.A.
46.6
46.6
6.6
33.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
6.6
20
N.A.
0
100
26.6
100
N.A.
60
53.3
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
49
42.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66
62.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
31
8
8
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
8
8
24
16
24
8
8
0
% D
% Glu:
0
0
8
8
0
0
0
8
24
31
0
16
0
8
16
% E
% Phe:
16
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
47
24
0
0
0
16
0
0
8
0
0
0
8
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
39
% I
% Lys:
0
0
8
8
8
16
24
0
0
16
8
8
8
47
8
% K
% Leu:
8
8
8
8
8
0
8
0
0
0
31
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
8
8
8
8
8
0
8
16
0
0
% N
% Pro:
0
8
0
8
47
8
8
8
39
24
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
16
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
24
8
0
% R
% Ser:
8
0
24
8
8
16
24
24
8
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
16
8
8
0
0
0
0
24
0
0
0
% T
% Val:
0
0
0
0
0
24
0
8
0
0
8
0
8
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
8
0
0
0
0
0
0
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _