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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR3 All Species: 55.45
Human Site: S220 Identified Species: 81.33
UniProt: P61158 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61158 NP_005712.1 418 47371 S220 V G I P P E Q S L E T A K A V
Chimpanzee Pan troglodytes XP_001143822 413 46798 S220 V G I P P E Q S L E T A K A I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853309 565 63553 S367 V G I P P E Q S L E T A K A V
Cat Felis silvestris
Mouse Mus musculus Q99JY9 418 47339 S220 V G I P P E Q S L E T A K A V
Rat Rattus norvegicus XP_342612 418 47616 S220 V G I P P E Q S L E T A K A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513007 482 55165 S284 V G I P P E Q S L E T A K A I
Chicken Gallus gallus Q90WD0 418 47403 S220 V G I P P E Q S L E T A K A V
Frog Xenopus laevis P10995 377 41970 G184 I M R L D L A G R D L T D Y L
Zebra Danio Brachydanio rerio NP_001003944 418 47376 S220 V G I P P E Q S L E T A K A V
Tiger Blowfish Takifugu rubipres O73723 418 47447 S220 V G I P P E Q S L E T A K A V
Fruit Fly Dros. melanogaster P32392 418 47014 S220 V G I P P E Q S L E T A K A I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4I0 425 48069 S227 H T I P A E Q S Y E V A K M I
Sea Urchin Strong. purpuratus XP_780265 418 47124 S220 P G I P P E Q S L E T A K A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAF1 427 47641 S229 E N I P P E D S F D V A R K V
Baker's Yeast Sacchar. cerevisiae P47117 449 49523 S255 E R G E A D T S L R T A E K I
Red Bread Mold Neurospora crassa P78712 439 47833 S242 D R G E P D S S L K T A Q E I
Conservation
Percent
Protein Identity: 100 84.6 N.A. 73.6 N.A. 99.7 91.1 N.A. 78.2 98.5 37.3 97.3 96.6 80.6 N.A. 76 84.6
Protein Similarity: 100 91.8 N.A. 73.8 N.A. 100 96.4 N.A. 83.4 99.7 52.6 99.2 99.5 90.6 N.A. 85.1 92.5
P-Site Identity: 100 93.3 N.A. 100 N.A. 100 93.3 N.A. 93.3 100 0 100 100 93.3 N.A. 53.3 86.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 20 100 100 100 N.A. 60 93.3
Percent
Protein Identity: N.A. N.A. N.A. 58.7 59.2 61
Protein Similarity: N.A. N.A. N.A. 74.9 69.2 72.4
P-Site Identity: N.A. N.A. N.A. 46.6 26.6 33.3
P-Site Similarity: N.A. N.A. N.A. 60 46.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 7 0 0 0 0 94 0 69 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 7 13 7 0 0 13 0 0 7 0 0 % D
% Glu: 13 0 0 13 0 82 0 0 0 75 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 69 13 0 0 0 0 7 0 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 82 0 0 0 0 0 0 0 0 0 0 0 50 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 0 0 75 13 0 % K
% Leu: 0 0 0 7 0 7 0 0 82 0 7 0 0 0 7 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 82 82 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 75 0 0 0 0 0 7 0 0 % Q
% Arg: 0 13 7 0 0 0 0 0 7 7 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 0 7 94 0 0 0 0 0 0 0 % S
% Thr: 0 7 0 0 0 0 7 0 0 0 82 7 0 0 0 % T
% Val: 63 0 0 0 0 0 0 0 0 0 13 0 0 0 44 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _