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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR3 All Species: 52.73
Human Site: Y202 Identified Species: 77.33
UniProt: P61158 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61158 NP_005712.1 418 47371 Y202 I A G R D I T Y F I Q Q L L R
Chimpanzee Pan troglodytes XP_001143822 413 46798 Y202 I A G R D I T Y F I Q Q L L R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853309 565 63553 Y349 I A G R D I T Y F I Q Q L L R
Cat Felis silvestris
Mouse Mus musculus Q99JY9 418 47339 Y202 I A G R D I T Y F I Q Q L L R
Rat Rattus norvegicus XP_342612 418 47616 Y202 I A G R D I T Y F I Q Q L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513007 482 55165 Y266 I A G R D I T Y F I Q Q L L R
Chicken Gallus gallus Q90WD0 418 47403 Y202 I A G R D I T Y F I Q Q L L R
Frog Xenopus laevis P10995 377 41970 E169 T H N V P I Y E G Y A L P H A
Zebra Danio Brachydanio rerio NP_001003944 418 47376 Y202 I A G R D I T Y F T Q Q L L R
Tiger Blowfish Takifugu rubipres O73723 418 47447 Y202 I A G R D I T Y F T Q Q L L R
Fruit Fly Dros. melanogaster P32392 418 47014 S202 I A G R N I T S F I Q S L L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4I0 425 48069 Y209 I A G R D I T Y F I Q S L L R
Sea Urchin Strong. purpuratus XP_780265 418 47124 Y202 I A G R D I T Y F I Q Q L L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAF1 427 47641 Q214 K D V T L F I Q Q L M R E R G
Baker's Yeast Sacchar. cerevisiae P47117 449 49523 L240 I A G R D I T L F I Q S L L R
Red Bread Mold Neurospora crassa P78712 439 47833 Y227 I A G R D I T Y F V Q S L L R
Conservation
Percent
Protein Identity: 100 84.6 N.A. 73.6 N.A. 99.7 91.1 N.A. 78.2 98.5 37.3 97.3 96.6 80.6 N.A. 76 84.6
Protein Similarity: 100 91.8 N.A. 73.8 N.A. 100 96.4 N.A. 83.4 99.7 52.6 99.2 99.5 90.6 N.A. 85.1 92.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 6.6 93.3 93.3 80 N.A. 93.3 100
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 6.6 93.3 93.3 86.6 N.A. 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. 58.7 59.2 61
Protein Similarity: N.A. N.A. N.A. 74.9 69.2 72.4
P-Site Identity: N.A. N.A. N.A. 0 86.6 86.6
P-Site Similarity: N.A. N.A. N.A. 13.3 86.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 88 0 0 0 0 0 0 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 82 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 88 0 0 0 0 0 0 % F
% Gly: 0 0 88 0 0 0 0 0 7 0 0 0 0 0 7 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 88 0 0 0 0 94 7 0 0 69 0 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 7 0 0 7 0 7 0 7 88 88 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 7 0 88 63 0 0 0 % Q
% Arg: 0 0 0 88 0 0 0 0 0 0 0 7 0 7 88 % R
% Ser: 0 0 0 0 0 0 0 7 0 0 0 25 0 0 0 % S
% Thr: 7 0 0 7 0 0 88 0 0 13 0 0 0 0 0 % T
% Val: 0 0 7 7 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 75 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _