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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR2
All Species:
52.12
Human Site:
Y378
Identified Species:
76.44
UniProt:
P61160
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61160
NP_005713.1
394
44761
Y378
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Chimpanzee
Pan troglodytes
XP_001155450
449
50593
Y433
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001090768
384
43673
Y368
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Dog
Lupus familis
XP_866190
405
45693
Y389
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5M7U6
394
44715
Y378
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513439
408
45857
Y392
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Chicken
Gallus gallus
P53488
394
44683
Y378
F
W
M
T
R
Q
E
Y
Q
E
K
G
V
R
V
Frog
Xenopus laevis
Q7ZTP2
394
44643
Y378
F
W
M
T
R
Q
E
Y
Q
E
K
G
T
R
V
Zebra Danio
Brachydanio rerio
Q7SXW6
394
44603
Y378
F
W
M
T
R
E
E
Y
Q
E
K
G
T
R
V
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
Q356
A
S
L
S
T
F
Q
Q
M
W
I
S
K
Q
E
Fruit Fly
Dros. melanogaster
P45888
394
44684
Y378
F
W
M
S
K
Q
E
Y
Q
E
Q
G
L
K
V
Honey Bee
Apis mellifera
XP_392831
400
45184
Y384
V
W
I
T
R
E
E
Y
E
E
K
G
L
S
V
Nematode Worm
Caenorhab. elegans
P53489
395
44822
Y379
F
W
V
S
K
K
E
Y
E
E
G
G
I
A
R
Sea Urchin
Strong. purpuratus
XP_784353
393
44390
Y378
F
W
I
S
R
E
E
Y
E
E
K
G
L
K
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSD6
389
44337
A365
L
A
G
I
M
K
D
A
P
E
F
W
I
N
R
Baker's Yeast
Sacchar. cerevisiae
P32381
391
44055
H369
S
I
M
A
D
K
D
H
M
W
L
S
K
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
97.4
95.8
N.A.
N.A.
99.7
N.A.
85
98.9
98.2
96.9
46.4
81.4
78.2
75.6
87.3
Protein Similarity:
100
87.3
97.4
96.5
N.A.
N.A.
100
N.A.
87.7
99.4
99.4
99.2
63.7
92.3
90.5
89.6
94.6
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
93.3
86.6
0
66.6
60
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
93.3
93.3
26.6
100
86.6
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.6
67.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
79.9
78.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
82
0
19
88
0
0
0
0
13
% E
% Phe:
75
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
7
82
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
13
7
0
0
0
0
0
0
7
0
13
0
0
% I
% Lys:
0
0
0
0
13
19
0
0
0
0
69
0
13
13
0
% K
% Leu:
7
0
7
0
0
0
0
0
0
0
7
0
19
0
0
% L
% Met:
0
0
69
0
7
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
57
7
7
63
0
7
0
0
13
0
% Q
% Arg:
0
0
0
0
69
0
0
0
0
0
0
0
0
57
13
% R
% Ser:
7
7
0
25
0
0
0
0
0
0
0
13
0
7
0
% S
% Thr:
0
0
0
63
7
0
0
0
0
0
0
0
13
0
0
% T
% Val:
7
0
7
0
0
0
0
0
0
0
0
0
44
0
69
% V
% Trp:
0
82
0
0
0
0
0
0
0
13
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _