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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR1A All Species: 25.15
Human Site: Y203 Identified Species: 34.58
UniProt: P61163 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61163 NP_005727.1 376 42614 Y203 L Y L R K E G Y D F H S S S E
Chimpanzee Pan troglodytes XP_001155293 376 42274 V203 L L L R K E G V D F H T S A E
Rhesus Macaque Macaca mulatta XP_001101028 376 42275 V203 L L L R K E G V D F H T S A E
Dog Lupus familis XP_854473 376 42271 V203 L L L R K E G V D F H T S A E
Cat Felis silvestris
Mouse Mus musculus Q8R5C5 376 42263 A203 L L L R K E G A D F H T S A E
Rat Rattus norvegicus P68035 377 42000 Y200 K I L T E R G Y S F V T T A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509975 345 38928 M176 P I Y E G F A M P H S I M R I
Chicken Gallus gallus P08023 377 41976 Y200 K I L S E R G Y S F V T T A E
Frog Xenopus laevis P10995 377 41970 Y200 K I L T E R G Y S F V T T A E
Zebra Danio Brachydanio rerio NP_998537 376 42387 Y203 L L L R K E G Y D F H T S A E
Tiger Blowfish Takifugu rubipres P53480 377 41956 Y200 K I L T E R G Y S F V T T A E
Fruit Fly Dros. melanogaster P45889 376 42701 F203 T L I R R E G F N F R S T A E
Honey Bee Apis mellifera XP_623834 376 42650 I203 L L L R K E G I N F R T T A E
Nematode Worm Caenorhab. elegans NP_497108 374 42053 Y202 V L L R R E G Y E F H R S N E
Sea Urchin Strong. purpuratus XP_796462 375 42304 F202 L L L R K E G F D F H T S A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P53492 377 41717 Y200 K I L T E R G Y M F T T T A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P38673 380 42364 Y201 T L L R K S G Y V F H T S A E
Conservation
Percent
Protein Identity: 100 90.1 90.9 90.9 N.A. 91.2 53.3 N.A. 91.4 53 53 93 53.3 79.2 84.5 69.9 88.3
Protein Similarity: 100 97.6 97.6 97.6 N.A. 97.6 74.2 N.A. 91.4 74.2 74.2 98.1 74.2 92 94.1 84.8 94.9
P-Site Identity: 100 73.3 73.3 73.3 N.A. 73.3 33.3 N.A. 0 33.3 33.3 80 33.3 40 53.3 60 73.3
P-Site Similarity: 100 86.6 86.6 86.6 N.A. 86.6 60 N.A. 0 60 60 93.3 60 80 80 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 54.1 N.A. 63.1
Protein Similarity: N.A. N.A. N.A. 75.8 N.A. 81
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. 60
P-Site Similarity: N.A. N.A. N.A. 60 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 6 6 0 0 0 0 0 83 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % D
% Glu: 0 0 0 6 30 59 0 0 6 0 0 0 0 0 95 % E
% Phe: 0 0 0 0 0 6 0 12 0 95 0 0 0 0 0 % F
% Gly: 0 0 0 0 6 0 95 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 6 53 0 0 0 0 % H
% Ile: 0 36 6 0 0 0 0 6 0 0 0 6 0 0 6 % I
% Lys: 30 0 0 0 53 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 48 59 89 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 6 6 0 0 0 6 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 0 0 6 0 % N
% Pro: 6 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 65 12 30 0 0 0 0 12 6 0 6 0 % R
% Ser: 0 0 0 6 0 6 0 0 24 0 6 12 53 6 0 % S
% Thr: 12 0 0 24 0 0 0 0 0 0 6 77 42 0 0 % T
% Val: 6 0 0 0 0 0 0 18 6 0 24 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 6 0 0 0 0 53 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _