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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCE1
All Species:
36.36
Human Site:
T437
Identified Species:
57.14
UniProt:
P61221
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61221
NP_001035809.1
599
67314
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Chimpanzee
Pan troglodytes
XP_001147081
599
67141
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Rhesus Macaque
Macaca mulatta
XP_001095891
596
66830
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Dog
Lupus familis
XP_532679
599
67310
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001101916
599
67282
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514246
599
67394
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Chicken
Gallus gallus
NP_001006440
599
67337
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Frog
Xenopus laevis
NP_001080761
599
67517
T437
E
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Zebra Danio
Brachydanio rerio
NP_998718
599
67269
T437
D
K
I
R
D
A
Y
T
H
P
Q
F
V
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648272
611
69280
V445
D
K
I
R
D
A
Y
V
H
P
Q
F
I
A
D
Honey Bee
Apis mellifera
XP_623630
608
68415
V446
E
K
I
R
D
A
Y
V
H
P
Q
F
V
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203141
586
66508
V424
A
K
I
R
D
S
Y
V
H
P
Q
F
A
T
D
Poplar Tree
Populus trichocarpa
XP_002328845
603
68059
M441
S
K
I
R
D
S
Y
M
H
P
Q
F
V
S
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LPJ4
605
68371
M443
Q
K
I
R
D
S
Y
M
H
P
Q
F
M
S
D
Baker's Yeast
Sacchar. cerevisiae
Q03195
608
68322
L443
K
K
I
R
G
Q
F
L
N
P
Q
F
Q
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
98.1
99.8
N.A.
N.A.
99.8
N.A.
99.1
98.8
93.3
90.3
N.A.
75.7
79.7
N.A.
77.3
Protein Similarity:
100
98
98.5
100
N.A.
N.A.
100
N.A.
100
99.5
97.5
95.6
N.A.
86.4
88.9
N.A.
86.8
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
100
93.3
N.A.
73.3
93.3
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
100
100
N.A.
86.6
93.3
N.A.
80
Percent
Protein Identity:
75.9
N.A.
N.A.
75.3
68
N.A.
Protein Similarity:
86.5
N.A.
N.A.
85.9
82.7
N.A.
P-Site Identity:
73.3
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
93.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
74
0
0
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
94
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
100
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
94
0
0
0
0
0
0
% H
% Ile:
0
0
100
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
0
0
0
100
0
7
0
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
20
0
0
0
0
0
0
0
14
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
0
0
0
80
0
% T
% Val:
0
0
0
0
0
0
0
20
0
0
0
0
74
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
94
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _