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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAP2B All Species: 24.55
Human Site: S127 Identified Species: 38.57
UniProt: P61225 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61225 NP_002877.2 183 20504 S127 L E G E R E V S Y G E G K A L
Chimpanzee Pan troglodytes XP_001140638 589 63249 S533 L E G E R E V S Y G E G K A L
Rhesus Macaque Macaca mulatta XP_001088490 184 20704 S128 L E S E R E V S S N E G R A L
Dog Lupus familis XP_534168 335 38190 S279 L E S E R E V S S N E G R A L
Cat Felis silvestris
Mouse Mus musculus Q8BU31 183 20726 M127 L E P E R E V M S S E G R A L
Rat Rattus norvegicus P61227 183 20486 S127 L E G E R E V S Y G E G K A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514804 244 27079 L127 L E S E R E V L S A E G R A L
Chicken Gallus gallus XP_001233104 403 43650 S347 L E S E R E V S S N E G R A L
Frog Xenopus laevis Q7ZXH7 184 20815 K128 E D E R V V G K E Q G Q N L A
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 K128 E D E R V V G K E Q G Q N L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 G127 L E E E R V V G K E L G K N L
Honey Bee Apis mellifera XP_001120003 181 20317 Q123 N K L D L E H Q R E V D T A E
Nematode Worm Caenorhab. elegans NP_506707 181 20375 S121 V G N K C D L S H Q R Q V R S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 V128 I N E R V I S V E E G I E V S
Red Bread Mold Neurospora crassa Q01387 229 25331 S151 R V T E R E V S T Q E G H A L
Conservation
Percent
Protein Identity: 100 31 89.1 47.7 N.A. 85.7 100 N.A. 67.2 40.6 61.4 61.9 N.A. 60.8 70.4 68.3 N.A.
Protein Similarity: 100 31 93.4 51.3 N.A. 92.9 100 N.A. 71.3 42.9 77.1 77.1 N.A. 77.7 83.6 80.8 N.A.
P-Site Identity: 100 100 73.3 73.3 N.A. 66.6 100 N.A. 66.6 73.3 0 0 N.A. 53.3 13.3 6.6 N.A.
P-Site Similarity: 100 100 80 80 N.A. 73.3 100 N.A. 73.3 80 6.6 6.6 N.A. 53.3 26.6 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.2 40.6
Protein Similarity: N.A. N.A. N.A. N.A. 52.2 56.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 60
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 0 0 0 67 14 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 0 7 0 0 0 0 0 7 0 0 0 % D
% Glu: 14 60 27 67 0 67 0 0 20 20 60 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 20 0 0 0 14 7 0 20 20 67 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 0 7 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 7 0 7 0 0 0 14 7 0 0 0 27 0 0 % K
% Leu: 60 0 7 0 7 0 7 7 0 0 7 0 0 14 67 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 7 7 7 0 0 0 0 0 0 20 0 0 14 7 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 27 0 20 0 0 0 % Q
% Arg: 7 0 0 20 67 0 0 0 7 0 7 0 34 7 0 % R
% Ser: 0 0 27 0 0 0 7 54 34 7 0 0 0 0 14 % S
% Thr: 0 0 7 0 0 0 0 0 7 0 0 0 7 0 0 % T
% Val: 7 7 0 0 20 20 67 7 0 0 7 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _