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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAX All Species: 35.15
Human Site: S151 Identified Species: 64.44
UniProt: P61244 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61244 NP_002373.3 160 18275 S151 S E P E E P Q S R K K L R M E
Chimpanzee Pan troglodytes XP_510008 607 66567 S598 S E P E E P Q S R K K L R M E
Rhesus Macaque Macaca mulatta XP_001103369 103 12080 L95 L K R Q N A L L E Q Q G E S K
Dog Lupus familis XP_866469 165 18813 S156 S E P E E P Q S R K K L R M E
Cat Felis silvestris
Mouse Mus musculus P28574 160 18178 S151 S E P E E P Q S R K K L R M E
Rat Rattus norvegicus P52164 160 18253 N151 S E P E E P Q N R K K L R M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514941 258 29073 S249 S E P E E P Q S R K K L R M E
Chicken Gallus gallus P52162 160 18165 S151 S E P D E P Q S R K K L R M E
Frog Xenopus laevis Q07016 163 18666 S154 S E T E E P Q S R K K L R M D
Zebra Danio Brachydanio rerio P52161 165 18710 T156 S E P E E Q R T R K K H R P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91664 161 18512 S150 E D L D Q D F S R R N K K M K
Honey Bee Apis mellifera XP_623530 171 19491 Q160 E T S R T V R Q S K K L K V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792474 181 20639 S170 L K G E H S G S S K S S K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.3 64.3 96.9 N.A. 98.1 98.7 N.A. 58.5 95.6 73 80.6 N.A. 44.7 54.9 N.A. 49.1
Protein Similarity: 100 26.3 64.3 96.9 N.A. 98.1 99.3 N.A. 60.4 98.7 78.5 86 N.A. 69.5 69.5 N.A. 63.5
P-Site Identity: 100 100 0 100 N.A. 100 93.3 N.A. 100 93.3 86.6 66.6 N.A. 20 20 N.A. 20
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 100 100 93.3 80 N.A. 60 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 16 0 8 0 0 0 0 0 0 0 0 8 % D
% Glu: 16 70 0 70 70 0 0 0 8 0 0 0 8 0 62 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 0 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 0 0 0 0 0 0 0 85 77 8 24 8 24 % K
% Leu: 16 0 8 0 0 0 8 8 0 0 0 70 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % M
% Asn: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 62 0 0 62 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 8 8 8 62 8 0 8 8 0 0 0 0 % Q
% Arg: 0 0 8 8 0 0 16 0 77 8 0 0 70 0 0 % R
% Ser: 70 0 8 0 0 8 0 70 16 0 8 8 0 8 0 % S
% Thr: 0 8 8 0 8 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _