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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1B
All Species:
47.88
Human Site:
Y133
Identified Species:
81.03
UniProt:
P61266
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61266
NP_443106.1
288
33245
Y133
F
V
E
V
M
T
E
Y
N
A
T
Q
S
K
Y
Chimpanzee
Pan troglodytes
XP_001146812
288
32492
Y134
F
V
E
V
M
S
E
Y
N
A
T
Q
S
D
Y
Rhesus Macaque
Macaca mulatta
XP_001103901
336
38070
Y181
F
V
E
V
M
T
E
Y
N
A
T
Q
S
K
Y
Dog
Lupus familis
XP_547038
348
39606
Y141
F
V
E
V
M
T
E
Y
N
A
T
Q
S
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
Y134
F
V
E
V
M
S
E
Y
N
A
T
Q
S
D
Y
Rat
Rattus norvegicus
P32851
288
33049
Y134
F
V
E
V
M
S
E
Y
N
A
T
Q
S
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990405
282
32496
Y126
V
R
E
V
M
T
E
Y
N
A
T
Q
S
K
Y
Frog
Xenopus laevis
NP_001086322
286
32704
Y132
F
V
D
V
M
T
K
Y
N
E
A
Q
V
D
F
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
Y133
F
V
E
V
M
T
E
Y
N
T
T
Q
S
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y137
F
V
E
V
M
T
E
Y
N
R
T
Q
T
D
Y
Honey Bee
Apis mellifera
XP_393760
291
33455
Y138
F
V
E
V
M
T
E
Y
N
R
T
Q
T
D
Y
Nematode Worm
Caenorhab. elegans
O16000
291
33234
Y135
F
V
E
V
M
T
D
Y
N
K
T
Q
T
D
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
M142
G
K
K
L
K
D
M
M
D
D
F
Q
R
L
R
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
Y133
F
L
K
L
I
Q
D
Y
R
I
I
D
S
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
85.1
75.5
N.A.
84
83.6
N.A.
N.A.
84.7
62.5
96.8
N.A.
68.7
66.3
59.1
N.A.
Protein Similarity:
100
88.1
85.7
78.1
N.A.
94.4
94
N.A.
N.A.
87.5
84
98.2
N.A.
82.1
79
78.3
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
53.3
93.3
N.A.
80
80
73.3
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
73.3
93.3
N.A.
86.6
86.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.8
49.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
15
0
8
8
0
8
0
50
0
% D
% Glu:
0
0
79
0
0
0
72
0
0
8
0
0
0
0
0
% E
% Phe:
86
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
8
15
0
8
0
8
0
0
8
0
0
0
36
0
% K
% Leu:
0
8
0
15
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
86
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
86
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
93
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
15
0
0
8
0
8
% R
% Ser:
0
0
0
0
0
22
0
0
0
0
0
0
65
0
0
% S
% Thr:
0
0
0
0
0
65
0
0
0
8
79
0
22
0
0
% T
% Val:
8
79
0
86
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _