KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF12
All Species:
13.94
Human Site:
S195
Identified Species:
34.07
UniProt:
P61328
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61328
NP_004104.3
243
27399
S195
R
V
K
K
T
K
P
S
S
H
F
V
P
K
P
Chimpanzee
Pan troglodytes
XP_001161806
207
23230
S160
V
K
K
T
K
P
S
S
H
F
V
P
K
P
I
Rhesus Macaque
Macaca mulatta
XP_001094765
243
27385
S195
R
V
K
K
T
K
T
S
S
H
F
V
P
K
P
Dog
Lupus familis
XP_542656
247
27149
A193
R
V
K
K
T
K
P
A
A
H
F
L
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P70379
247
27746
A193
R
V
K
K
T
K
P
A
A
H
F
L
P
K
P
Rat
Rattus norvegicus
P61150
243
27381
S195
R
V
K
K
T
K
P
S
S
H
F
V
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511465
243
27351
S195
R
V
K
K
T
K
P
S
S
H
F
V
P
K
P
Chicken
Gallus gallus
P48801
220
25031
R173
R
R
G
F
K
T
R
R
T
Q
K
S
S
L
F
Frog
Xenopus laevis
Q91875
209
23644
R162
K
H
A
D
T
G
R
R
Y
Y
V
A
L
N
K
Zebra Danio
Brachydanio rerio
P48802
256
28905
A200
K
T
R
S
T
D
K
A
S
L
F
L
P
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.1
99.5
69.2
N.A.
72
100
N.A.
98.7
29.6
28.8
26.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.4
99.5
79.3
N.A.
85
100
N.A.
99.5
49.3
48.1
46
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
80
N.A.
80
100
N.A.
100
6.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
100
N.A.
100
100
N.A.
100
13.3
20
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
30
20
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
70
0
0
0
10
% F
% Gly:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
10
60
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
20
10
70
60
20
60
10
0
0
0
10
0
10
60
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
30
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
50
0
0
0
0
10
70
10
60
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
70
10
10
0
0
0
20
20
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
10
0
0
10
50
50
0
0
10
10
0
0
% S
% Thr:
0
10
0
10
80
10
10
0
10
0
0
0
0
0
0
% T
% Val:
10
60
0
0
0
0
0
0
0
0
20
40
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _