KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISL1
All Species:
23.64
Human Site:
S321
Identified Species:
47.27
UniProt:
P61371
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61371
NP_002193.2
349
39036
S321
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S337
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Rhesus Macaque
Macaca mulatta
XP_001104982
360
39837
G332
F
S
E
S
G
S
L
G
N
S
S
G
S
D
V
Dog
Lupus familis
XP_853721
346
38714
S318
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXV0
359
39637
G331
F
S
E
S
G
S
L
G
N
S
S
G
S
D
V
Rat
Rattus norvegicus
P61374
349
39017
S321
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508080
665
71117
S637
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Chicken
Gallus gallus
P50211
349
39015
S321
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Frog
Xenopus laevis
P29674
403
44916
A369
G
S
M
H
S
M
S
A
E
V
F
G
Q
S
P
Zebra Danio
Brachydanio rerio
P53405
349
39162
S321
F
S
E
G
G
P
G
S
N
S
T
G
S
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476775
534
58026
N382
P
A
F
Q
Q
L
V
N
Q
M
H
G
Y
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781774
401
45310
Q356
F
S
E
Q
S
L
G
Q
T
T
L
V
K
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.7
73.6
99.1
N.A.
72.1
100
N.A.
52
99.4
30
97.9
N.A.
43.2
N.A.
N.A.
62
Protein Similarity:
100
46.5
83.8
99.1
N.A.
82.4
100
N.A.
52.3
100
47.3
99.1
N.A.
51.5
N.A.
N.A.
69.8
P-Site Identity:
100
13.3
60
100
N.A.
60
100
N.A.
100
100
13.3
100
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
20
73.3
100
N.A.
73.3
100
N.A.
100
100
20
100
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% D
% Glu:
0
0
75
0
0
0
0
0
9
9
0
0
0
50
0
% E
% Phe:
75
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
9
0
0
59
67
0
59
17
0
0
0
84
0
0
0
% G
% His:
0
0
0
9
9
9
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
9
0
0
0
17
17
0
0
0
9
0
0
0
9
% L
% Met:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
67
0
0
0
0
0
0
% N
% Pro:
17
0
9
0
0
50
9
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
17
9
0
0
9
9
0
0
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
84
0
17
17
17
9
59
9
67
17
0
67
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
9
50
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _