KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0D1
All Species:
53.03
Human Site:
Y274
Identified Species:
77.78
UniProt:
P61421
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61421
NP_004682.2
351
40329
Y274
V
A
D
Y
Y
P
E
Y
K
L
L
F
E
G
A
Chimpanzee
Pan troglodytes
XP_001163802
351
40445
Y274
V
A
D
Y
Y
P
E
Y
K
L
L
F
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001082286
350
40384
Y274
V
A
D
H
Y
G
V
Y
K
P
L
F
E
A
V
Dog
Lupus familis
XP_536816
351
40383
Y274
V
A
D
Y
Y
P
E
Y
K
L
L
F
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P51863
351
40283
Y274
V
A
D
Y
Y
P
E
Y
K
L
L
F
E
G
A
Rat
Rattus norvegicus
Q5FVL0
350
40501
Y274
V
A
D
N
Y
G
V
Y
K
P
L
F
D
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHL0
351
40381
Y274
V
A
D
Y
Y
A
E
Y
K
A
V
F
E
G
V
Frog
Xenopus laevis
NP_001080200
351
40190
Y274
V
A
D
Y
Y
P
E
Y
K
L
L
F
E
G
A
Zebra Danio
Brachydanio rerio
NP_955914
350
40172
Y273
V
A
E
Y
Y
P
E
Y
K
L
L
F
E
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4P5
350
39833
Y273
V
A
E
Y
Y
A
E
Y
A
A
L
F
D
G
S
Honey Bee
Apis mellifera
XP_393438
348
39548
Y271
V
A
E
Y
F
A
E
Y
S
A
L
F
E
G
A
Nematode Worm
Caenorhab. elegans
NP_491515
348
39919
Y271
V
C
E
F
Y
S
D
Y
K
P
L
F
E
G
S
Sea Urchin
Strong. purpuratus
XP_779935
348
39778
Y271
V
A
E
S
Y
P
E
Y
K
M
L
F
E
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LJI5
351
40773
Y274
V
M
E
K
Y
P
P
Y
Q
A
I
F
S
K
M
Baker's Yeast
Sacchar. cerevisiae
P32366
345
39772
Y275
A
L
A
N
V
Y
E
Y
R
G
F
L
E
T
G
Red Bread Mold
Neurospora crassa
P53659
364
40989
Y274
A
V
E
G
V
A
D
Y
K
S
F
F
D
A
A
Conservation
Percent
Protein Identity:
100
97.4
68
99.4
N.A.
99.7
66.3
N.A.
N.A.
78.9
94
94.3
N.A.
79.7
79.1
74.3
78.9
Protein Similarity:
100
98
83.7
99.7
N.A.
100
81.7
N.A.
N.A.
88.8
96.8
97.4
N.A.
90.3
89.4
87.4
90
P-Site Identity:
100
100
60
100
N.A.
100
53.3
N.A.
N.A.
73.3
100
93.3
N.A.
60
66.6
53.3
80
P-Site Similarity:
100
100
66.6
100
N.A.
100
60
N.A.
N.A.
80
100
100
N.A.
80
80
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.7
46.4
51.3
Protein Similarity:
N.A.
N.A.
N.A.
71.7
66.9
70.3
P-Site Identity:
N.A.
N.A.
N.A.
33.3
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
75
7
0
0
25
0
0
7
25
0
0
0
19
57
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
13
0
0
0
0
0
19
0
0
% D
% Glu:
0
0
44
0
0
0
69
0
0
0
0
0
75
0
0
% E
% Phe:
0
0
0
7
7
0
0
0
0
0
13
94
0
0
0
% F
% Gly:
0
0
0
7
0
13
0
0
0
7
0
0
0
69
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
75
0
0
0
0
7
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
38
75
7
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
7
% M
% Asn:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
7
0
0
19
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
7
0
0
7
7
0
0
7
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
88
7
0
0
13
0
13
0
0
0
7
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
57
82
7
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _