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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPE1 All Species: 39.7
Human Site: S64 Identified Species: 72.78
UniProt: P61604 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61604 NP_002148.1 102 10932 S64 G G E I Q P V S V K V G D K V
Chimpanzee Pan troglodytes XP_509315 102 11232 S64 G R E I Q P V S V K V G D K V
Rhesus Macaque Macaca mulatta XP_001118014 281 30135 S243 G G E I Q P V S V K V G D K A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64433 102 10944 S64 S G E I E P V S V K V G D K V
Rat Rattus norvegicus P26772 102 10883 S64 G G E I Q P V S V K V G D K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516202 210 22501 S172 S G E L Q P V S V E V G D K V
Chicken Gallus gallus NP_990398 102 11064 S64 D G E I H P V S V K V G E K V
Frog Xenopus laevis NP_001084708 102 11079 S64 T G D I Q P V S V K V G D K I
Zebra Danio Brachydanio rerio NP_571601 100 11001 C62 D G K V I P V C V K V G D K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624910 104 11385 S65 K G E H I P L S I K V G D I V
Nematode Worm Caenorhab. elegans NP_497428 108 11831 T71 K G E L V A L T V K P G D R V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P34893 98 10794 S59 D G K L I P V S V K E G D T V
Baker's Yeast Sacchar. cerevisiae P38910 106 11354 Q66 N G N K V V P Q V K V G D Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 35.5 N.A. N.A. 96 99 N.A. 45.7 87.2 88.2 81.3 N.A. N.A. 59.6 59.2 N.A.
Protein Similarity: 100 94.1 35.9 N.A. N.A. 97 99 N.A. 48 97 96 89.2 N.A. N.A. 74 75.9 N.A.
P-Site Identity: 100 93.3 93.3 N.A. N.A. 86.6 100 N.A. 80 80 80 66.6 N.A. N.A. 60 46.6 N.A.
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 93.3 100 N.A. 93.3 86.6 93.3 80 N.A. N.A. 73.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 67.6 65 N.A.
P-Site Identity: N.A. N.A. N.A. 60 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 24 0 8 0 0 0 0 0 0 0 0 0 93 0 0 % D
% Glu: 0 0 70 0 8 0 0 0 0 8 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 31 93 0 0 0 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 54 24 0 0 0 8 0 0 0 0 8 8 % I
% Lys: 16 0 16 8 0 0 0 0 0 93 0 0 0 70 0 % K
% Leu: 0 0 0 24 0 0 16 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 85 8 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 47 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 16 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % T
% Val: 0 0 0 8 16 8 77 0 93 0 85 0 0 0 85 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _