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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPE1 All Species: 48.18
Human Site: Y76 Identified Species: 88.33
UniProt: P61604 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61604 NP_002148.1 102 10932 Y76 D K V L L P E Y G G T K V V L
Chimpanzee Pan troglodytes XP_509315 102 11232 Y76 D K V L L P E Y G G T K V V L
Rhesus Macaque Macaca mulatta XP_001118014 281 30135 Y255 D K A L L P E Y G G T K V V L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64433 102 10944 Y76 D K V L L P E Y G G T K V V L
Rat Rattus norvegicus P26772 102 10883 Y76 D K V L L P E Y G G T K V V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516202 210 22501 Y184 D K V L L P E Y G G T K V V L
Chicken Gallus gallus NP_990398 102 11064 Y76 E K V L L P E Y G G T K I V L
Frog Xenopus laevis NP_001084708 102 11079 Y76 D K I L L P E Y G G T K V V L
Zebra Danio Brachydanio rerio NP_571601 100 11001 Y74 D K V L L P E Y G G T K V M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624910 104 11385 Y77 D I V L L P E Y G G T K V E F
Nematode Worm Caenorhab. elegans NP_497428 108 11831 Y83 D R V L L P E Y G G T K V V V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P34893 98 10794 Y71 D T V L L P E Y G G T Q V K L
Baker's Yeast Sacchar. cerevisiae P38910 106 11354 F78 D Q V L I P Q F G G S T I K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 35.5 N.A. N.A. 96 99 N.A. 45.7 87.2 88.2 81.3 N.A. N.A. 59.6 59.2 N.A.
Protein Similarity: 100 94.1 35.9 N.A. N.A. 97 99 N.A. 48 97 96 89.2 N.A. N.A. 74 75.9 N.A.
P-Site Identity: 100 100 93.3 N.A. N.A. 100 100 N.A. 100 86.6 93.3 93.3 N.A. N.A. 80 86.6 N.A.
P-Site Similarity: 100 100 93.3 N.A. N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. 80 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 67.6 65 N.A.
P-Site Identity: N.A. N.A. N.A. 80 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 93 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 100 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 0 0 0 0 0 0 0 16 0 0 % I
% Lys: 0 70 0 0 0 0 0 0 0 0 0 85 0 16 0 % K
% Leu: 0 0 0 100 93 0 0 0 0 0 0 0 0 0 85 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 0 0 8 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 93 8 0 0 0 % T
% Val: 0 0 85 0 0 0 0 0 0 0 0 0 85 70 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _