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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPE1 All Species: 42.73
Human Site: Y88 Identified Species: 78.33
UniProt: P61604 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61604 NP_002148.1 102 10932 Y88 V V L D D K D Y F L F R D G D
Chimpanzee Pan troglodytes XP_509315 102 11232 Y88 V V L D D K D Y F L F R D G D
Rhesus Macaque Macaca mulatta XP_001118014 281 30135 Y267 V V L D D K D Y F L F R D G D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64433 102 10944 Y88 V V L D D K D Y F L F R D S D
Rat Rattus norvegicus P26772 102 10883 Y88 V V L D D K D Y F L F R D G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516202 210 22501 Y196 V V L E D K D Y F L F R D G D
Chicken Gallus gallus NP_990398 102 11064 Y88 I V L E D K D Y Y L F R D G D
Frog Xenopus laevis NP_001084708 102 11079 Y88 V V L E D K D Y F L F R D G D
Zebra Danio Brachydanio rerio NP_571601 100 11001 Y86 V M L E D K D Y F L F R D A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624910 104 11385 E89 V E F E D N K E F H L F R E S
Nematode Worm Caenorhab. elegans NP_497428 108 11831 Y95 V V V E D K E Y S I F R E S D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P34893 98 10794 Y83 V K L G E N E Y H L F R D E D
Baker's Yeast Sacchar. cerevisiae P38910 106 11354 E90 I K L G N D D E V I L F R D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 35.5 N.A. N.A. 96 99 N.A. 45.7 87.2 88.2 81.3 N.A. N.A. 59.6 59.2 N.A.
Protein Similarity: 100 94.1 35.9 N.A. N.A. 97 99 N.A. 48 97 96 89.2 N.A. N.A. 74 75.9 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 93.3 100 N.A. 93.3 80 93.3 80 N.A. N.A. 20 53.3 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 100 N.A. 100 100 100 93.3 N.A. N.A. 26.6 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 67.6 65 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 39 85 8 77 0 0 0 0 0 77 8 85 % D
% Glu: 0 8 0 47 8 0 16 16 0 0 0 0 8 16 0 % E
% Phe: 0 0 8 0 0 0 0 0 70 0 85 16 0 0 0 % F
% Gly: 0 0 0 16 0 0 0 0 0 0 0 0 0 54 0 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % I
% Lys: 0 16 0 0 0 77 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 85 0 0 0 0 0 0 77 16 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 16 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 85 16 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 8 0 0 0 0 16 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 85 70 8 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 85 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _