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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC61A1
All Species:
46.97
Human Site:
S350
Identified Species:
73.81
UniProt:
P61619
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61619
NP_037468.1
476
52265
S350
Y
Y
L
S
P
P
E
S
F
G
S
V
L
E
D
Chimpanzee
Pan troglodytes
XP_516725
587
64427
S461
Y
Y
L
S
P
P
E
S
F
G
S
V
L
E
D
Rhesus Macaque
Macaca mulatta
XP_001098356
593
65043
S467
Y
Y
L
S
P
P
E
S
F
G
S
V
L
E
D
Dog
Lupus familis
XP_535191
551
60482
S425
Y
Y
L
S
P
P
E
S
M
G
A
I
F
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLR1
476
52229
S350
Y
Y
L
S
P
P
E
S
M
G
A
I
F
E
D
Rat
Rattus norvegicus
P61621
476
52246
S350
Y
Y
L
S
P
P
E
S
F
G
S
V
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506700
527
57384
S401
Y
Y
L
S
P
P
E
S
F
G
S
V
L
E
D
Chicken
Gallus gallus
XP_414364
577
63158
S451
Y
Y
L
S
P
P
E
S
F
S
S
V
L
E
D
Frog
Xenopus laevis
NP_001080244
476
52132
S350
Y
Y
L
S
P
P
E
S
F
G
S
V
L
D
D
Zebra Danio
Brachydanio rerio
Q90ZM2
476
52279
S350
Y
Y
L
S
P
P
E
S
F
G
S
V
L
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609034
476
52166
S350
Y
Y
L
S
P
P
E
S
V
G
H
I
L
T
D
Honey Bee
Apis mellifera
XP_001120255
476
52370
S350
Y
Y
L
S
P
P
E
S
V
G
H
I
L
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_802085
475
52232
N349
Y
Y
M
S
P
P
E
N
F
S
R
F
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32915
480
52918
L352
Y
I
Q
P
L
M
S
L
S
E
A
L
L
D
P
Red Bread Mold
Neurospora crassa
Q870W0
476
52293
K352
M
S
P
P
L
N
F
K
D
A
L
L
D
P
I
Conservation
Percent
Protein Identity:
100
81
80.2
80.9
N.A.
93.4
100
N.A.
89.9
81.9
97.9
97
N.A.
89.2
88
N.A.
89.2
Protein Similarity:
100
81
80.2
84
N.A.
97
100
N.A.
90.3
82.3
99.1
98.7
N.A.
94.9
95.1
N.A.
94.9
P-Site Identity:
100
100
100
73.3
N.A.
73.3
100
N.A.
100
93.3
93.3
93.3
N.A.
73.3
73.3
N.A.
60
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
100
N.A.
100
93.3
100
100
N.A.
80
86.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
55
64
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.5
80.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
0
7
20
87
% D
% Glu:
0
0
0
0
0
0
87
0
0
7
0
0
0
54
0
% E
% Phe:
0
0
0
0
0
0
7
0
60
0
0
7
14
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
74
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
27
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
0
80
0
14
0
0
7
0
0
7
14
80
0
0
% L
% Met:
7
0
7
0
0
7
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
14
87
87
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
7
0
87
0
0
7
80
7
14
54
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
14
0
0
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
94
87
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _