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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC61A1
All Species:
61.21
Human Site:
Y279
Identified Species:
96.19
UniProt:
P61619
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61619
NP_037468.1
476
52265
Y279
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Chimpanzee
Pan troglodytes
XP_516725
587
64427
Y390
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Rhesus Macaque
Macaca mulatta
XP_001098356
593
65043
Y396
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Dog
Lupus familis
XP_535191
551
60482
Y354
Y
R
G
Q
Y
S
S
Y
P
I
K
L
F
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLR1
476
52229
Y279
Y
R
G
Q
Y
S
S
Y
P
I
K
L
F
Y
T
Rat
Rattus norvegicus
P61621
476
52246
Y279
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506700
527
57384
Y330
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Chicken
Gallus gallus
XP_414364
577
63158
Y380
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Frog
Xenopus laevis
NP_001080244
476
52132
Y279
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Zebra Danio
Brachydanio rerio
Q90ZM2
476
52279
Y279
Y
R
G
Q
Y
N
T
Y
P
I
K
L
F
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609034
476
52166
Y279
Y
R
G
Q
Y
S
S
Y
P
I
K
L
F
Y
T
Honey Bee
Apis mellifera
XP_001120255
476
52370
Y279
Y
R
G
Q
Y
S
S
Y
P
I
K
L
F
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_802085
475
52232
Y278
Y
R
G
Q
Y
S
S
Y
P
I
K
L
F
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32915
480
52918
Y281
V
R
G
Q
I
G
I
Y
P
I
K
L
F
Y
T
Red Bread Mold
Neurospora crassa
Q870W0
476
52293
Y281
Q
R
G
A
R
G
S
Y
P
I
R
L
F
Y
T
Conservation
Percent
Protein Identity:
100
81
80.2
80.9
N.A.
93.4
100
N.A.
89.9
81.9
97.9
97
N.A.
89.2
88
N.A.
89.2
Protein Similarity:
100
81
80.2
84
N.A.
97
100
N.A.
90.3
82.3
99.1
98.7
N.A.
94.9
95.1
N.A.
94.9
P-Site Identity:
100
100
100
86.6
N.A.
86.6
100
N.A.
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
55
64
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.5
80.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% F
% Gly:
0
0
100
0
0
14
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
100
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
94
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% P
% Gln:
7
0
0
94
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
7
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
34
40
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
100
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
87
0
0
0
87
0
0
100
0
0
0
0
0
100
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _