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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VBP1 All Species: 18.79
Human Site: T48 Identified Species: 27.56
UniProt: P61758 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61758 NP_003363.1 197 22658 T48 P G N E T A D T V L K K L D E
Chimpanzee Pan troglodytes XP_521348 192 22192 T43 P G N E T A D T V L K K L D E
Rhesus Macaque Macaca mulatta XP_001098746 197 22579 T48 P G N E T A D T V L K K L D E
Dog Lupus familis XP_538210 197 22457 T48 P G N E T A D T V L K K L D E
Cat Felis silvestris
Mouse Mus musculus P61759 196 22417 T47 P G N E T A D T V L K K L D E
Rat Rattus norvegicus XP_001058594 186 20910 A45 P G N E S A D A A L R K L D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509257 359 40040 V124 P G N E T A D V V L K K L D E
Chicken Gallus gallus XP_420327 200 22423 V51 P G N E T A D V V L K K L D E
Frog Xenopus laevis NP_001080849 192 21936 A43 A G N E T A D A V L K K L D E
Zebra Danio Brachydanio rerio NP_001018460 195 22264 A44 P G N D T A D A V L R K L D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGP6 185 21332 L42 C E K V L Q R L D E Q H G K Y
Honey Bee Apis mellifera XP_624282 190 22139 K45 P E N E S A D K V L Q K L D E
Nematode Worm Caenorhab. elegans O18054 185 20866 Y44 E V V L R E K Y G K Y K Y V E
Sea Urchin Strong. purpuratus XP_797937 185 21011 E45 V V L K R L E E Q H Q K Y K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P57741 195 21447 A42 S G L D P N S A L A F H Q E R
Baker's Yeast Sacchar. cerevisiae P48363 199 23097 R44 C F N K F Q E R L S K Y K F M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 98.9 95.9 N.A. 96.4 71 N.A. 44.2 87 82.2 76.1 N.A. 49.2 53.2 35.5 58.8
Protein Similarity: 100 87.3 99.4 97.4 N.A. 96.9 83.2 N.A. 49.2 91 88.8 88.3 N.A. 69 75.6 59.9 77.6
P-Site Identity: 100 100 100 100 N.A. 100 73.3 N.A. 93.3 93.3 86.6 80 N.A. 0 73.3 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 86.6 N.A. 93.3 93.3 86.6 93.3 N.A. 6.6 86.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 40.1 41.7 N.A.
Protein Similarity: N.A. N.A. N.A. 62.4 61.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 69 0 25 7 7 0 0 0 0 0 % A
% Cys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 69 0 7 0 0 0 0 69 0 % D
% Glu: 7 13 0 63 0 7 13 7 0 7 0 0 0 7 75 % E
% Phe: 0 7 0 0 7 0 0 0 0 0 7 0 0 7 7 % F
% Gly: 0 69 0 0 0 0 0 0 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 13 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 13 0 0 7 7 0 7 57 82 7 13 0 % K
% Leu: 0 0 13 7 7 7 0 7 13 69 0 0 69 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 75 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 63 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 13 0 0 7 0 19 0 7 0 0 % Q
% Arg: 0 0 0 0 13 0 7 7 0 0 13 0 0 0 7 % R
% Ser: 7 0 0 0 13 0 7 0 0 7 0 0 0 0 0 % S
% Thr: 0 0 0 0 57 0 0 32 0 0 0 0 0 0 0 % T
% Val: 7 13 7 7 0 0 0 13 63 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 7 7 13 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _