Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VBP1 All Species: 39.09
Human Site: Y112 Identified Species: 57.33
UniProt: P61758 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61758 NP_003363.1 197 22658 Y112 F L L A D N L Y C K A S V P P
Chimpanzee Pan troglodytes XP_521348 192 22192 Y107 F L L A D N L Y C K A S V P P
Rhesus Macaque Macaca mulatta XP_001098746 197 22579 Y112 F L L A D N L Y C K A S V P P
Dog Lupus familis XP_538210 197 22457 Y112 F L L A D N L Y C K A S V P P
Cat Felis silvestris
Mouse Mus musculus P61759 196 22417 Y111 F L L A D N L Y C K A S V P P
Rat Rattus norvegicus XP_001058594 186 20910 F102 P H A M E T R F L L A D N L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509257 359 40040 Y258 Q T L E I L K Y M Q K K K E S
Chicken Gallus gallus XP_420327 200 22423 Y115 F L L A D N L Y C K A S V P P
Frog Xenopus laevis NP_001080849 192 21936 Y107 F M L A D N L Y C K A S V P P
Zebra Danio Brachydanio rerio NP_001018460 195 22264 Y108 F L L A D N V Y C K A S V P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGP6 185 21332 F98 F L L S D Q V F I K T L V P P
Honey Bee Apis mellifera XP_624282 190 22139 F102 S K E L E T Q F L L S E Q V Y
Nematode Worm Caenorhab. elegans O18054 185 20866 Y99 F L L S D D V Y T K A T V Q K
Sea Urchin Strong. purpuratus XP_797937 185 21011 Q100 T Q F L L S D Q V Y A K A S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P57741 195 21447 Y105 F E V S E G I Y S R A C I E D
Baker's Yeast Sacchar. cerevisiae P48363 199 23097 V109 T L Y T K A Q V D I P E D R A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 98.9 95.9 N.A. 96.4 71 N.A. 44.2 87 82.2 76.1 N.A. 49.2 53.2 35.5 58.8
Protein Similarity: 100 87.3 99.4 97.4 N.A. 96.9 83.2 N.A. 49.2 91 88.8 88.3 N.A. 69 75.6 59.9 77.6
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 13.3 100 93.3 93.3 N.A. 53.3 0 53.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 20 100 100 100 N.A. 73.3 20 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40.1 41.7 N.A.
Protein Similarity: N.A. N.A. N.A. 62.4 61.8 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 50 0 7 0 0 0 0 75 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 50 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 63 7 7 0 7 0 0 7 7 0 7 % D
% Glu: 0 7 7 7 19 0 0 0 0 0 0 13 0 13 0 % E
% Phe: 69 0 7 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 7 0 7 7 0 0 7 0 7 % I
% Lys: 0 7 0 0 7 0 7 0 0 63 7 13 7 0 7 % K
% Leu: 0 63 69 13 7 7 44 0 13 13 0 7 0 7 0 % L
% Met: 0 7 0 7 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 50 0 0 0 0 0 0 7 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 7 0 0 57 57 % P
% Gln: 7 7 0 0 0 7 13 7 0 7 0 0 7 7 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % R
% Ser: 7 0 0 19 0 7 0 0 7 0 7 50 0 7 7 % S
% Thr: 13 7 0 7 0 13 0 0 7 0 7 7 0 0 0 % T
% Val: 0 0 7 0 0 0 19 7 7 0 0 0 63 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 69 0 7 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _