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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPZ1 All Species: 37.58
Human Site: Y30 Identified Species: 63.59
UniProt: P61923 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61923 NP_057141.1 177 20198 Y30 G D R L F A K Y Y D D T Y P S
Chimpanzee Pan troglodytes XP_001156445 198 22357 Y30 G D R L F A K Y Y D D T Y P S
Rhesus Macaque Macaca mulatta XP_001109692 197 22177 Y50 G D R L F A K Y Y D D T Y P S
Dog Lupus familis XP_855951 177 20229 Y30 G D R L F A K Y Y D D T Y P S
Cat Felis silvestris
Mouse Mus musculus Q9JHH9 205 22916 Y58 G R R L L A K Y Y D D T F P S
Rat Rattus norvegicus NP_001101764 207 23249 Y60 G R R L L A K Y Y D D T F P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085450 177 20156 Y30 G E R L F A K Y Y D E T Y P T
Zebra Danio Brachydanio rerio NP_571583 177 20261 Y30 G E R L Y A K Y Y D D T Y P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648910 174 19918 Y27 N R I L A K Y Y D K N I L S T
Honey Bee Apis mellifera XP_623380 201 22791 Y54 N R I L A K Y Y D K N I F P T
Nematode Worm Caenorhab. elegans O17901 184 20738 D33 R V L A K Y Y D R T T F G T V
Sea Urchin Strong. purpuratus XP_785136 177 19813 Y30 G E R L L A K Y Y D D T F S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940S5 177 19597 D28 A V K Y Y S D D W P T N S A Q
Baker's Yeast Sacchar. cerevisiae P53600 189 21669 G36 P P H R S D E G H Q L L F N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 88.8 97.1 N.A. 64.3 63.7 N.A. N.A. N.A. 92.6 93.2 N.A. 59.3 59.2 53.2 64.9
Protein Similarity: 100 87.3 89.8 97.7 N.A. 74.1 73.9 N.A. N.A. N.A. 99.4 99.4 N.A. 85.3 78.6 77.1 88.1
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. N.A. N.A. 80 80 N.A. 13.3 20 0 66.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 100 100 N.A. 26.6 40 0 86.6
Percent
Protein Identity: N.A. N.A. N.A. 44.6 36.5 N.A.
Protein Similarity: N.A. N.A. N.A. 69.4 57.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 15 65 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 0 8 8 15 15 65 58 0 0 0 0 % D
% Glu: 0 22 0 0 0 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 36 0 0 0 0 0 0 8 36 0 0 % F
% Gly: 65 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 0 0 0 0 0 0 0 15 0 0 0 % I
% Lys: 0 0 8 0 8 15 65 0 0 15 0 0 0 0 0 % K
% Leu: 0 0 8 79 22 0 0 0 0 0 8 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 0 0 0 0 0 0 15 8 0 8 0 % N
% Pro: 8 8 0 0 0 0 0 0 0 8 0 0 0 65 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % Q
% Arg: 8 29 65 8 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 0 0 0 0 0 8 15 50 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 15 65 0 8 36 % T
% Val: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 15 8 22 79 65 0 0 0 43 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _