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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPZ1
All Species:
34.24
Human Site:
Y31
Identified Species:
57.95
UniProt:
P61923
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61923
NP_057141.1
177
20198
Y31
D
R
L
F
A
K
Y
Y
D
D
T
Y
P
S
V
Chimpanzee
Pan troglodytes
XP_001156445
198
22357
Y31
D
R
L
F
A
K
Y
Y
D
D
T
Y
P
S
V
Rhesus Macaque
Macaca mulatta
XP_001109692
197
22177
Y51
D
R
L
F
A
K
Y
Y
D
D
T
Y
P
S
V
Dog
Lupus familis
XP_855951
177
20229
Y31
D
R
L
F
A
K
Y
Y
D
D
T
Y
P
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHH9
205
22916
Y59
R
R
L
L
A
K
Y
Y
D
D
T
F
P
S
V
Rat
Rattus norvegicus
NP_001101764
207
23249
Y61
R
R
L
L
A
K
Y
Y
D
D
T
F
P
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085450
177
20156
Y31
E
R
L
F
A
K
Y
Y
D
E
T
Y
P
T
V
Zebra Danio
Brachydanio rerio
NP_571583
177
20261
Y31
E
R
L
Y
A
K
Y
Y
D
D
T
Y
P
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648910
174
19918
D28
R
I
L
A
K
Y
Y
D
K
N
I
L
S
T
L
Honey Bee
Apis mellifera
XP_623380
201
22791
D55
R
I
L
A
K
Y
Y
D
K
N
I
F
P
T
S
Nematode Worm
Caenorhab. elegans
O17901
184
20738
R34
V
L
A
K
Y
Y
D
R
T
T
F
G
T
V
K
Sea Urchin
Strong. purpuratus
XP_785136
177
19813
Y31
E
R
L
L
A
K
Y
Y
D
D
T
F
S
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940S5
177
19597
W29
V
K
Y
Y
S
D
D
W
P
T
N
S
A
Q
E
Baker's Yeast
Sacchar. cerevisiae
P53600
189
21669
H37
P
H
R
S
D
E
G
H
Q
L
L
F
N
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
88.8
97.1
N.A.
64.3
63.7
N.A.
N.A.
N.A.
92.6
93.2
N.A.
59.3
59.2
53.2
64.9
Protein Similarity:
100
87.3
89.8
97.7
N.A.
74.1
73.9
N.A.
N.A.
N.A.
99.4
99.4
N.A.
85.3
78.6
77.1
88.1
P-Site Identity:
100
100
100
100
N.A.
80
73.3
N.A.
N.A.
N.A.
80
80
N.A.
13.3
20
0
60
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
100
100
N.A.
33.3
40
0
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.6
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.4
57.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
65
0
0
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
0
0
8
8
15
15
65
58
0
0
0
0
0
% D
% Glu:
22
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
36
0
0
0
0
0
0
8
36
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% I
% Lys:
0
8
0
8
15
65
0
0
15
0
0
0
0
0
8
% K
% Leu:
0
8
79
22
0
0
0
0
0
8
8
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
8
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
65
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
29
65
8
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
0
0
0
0
8
15
50
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
15
65
0
8
36
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
58
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
15
8
22
79
65
0
0
0
43
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _