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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKIA All Species: 15.45
Human Site: S30 Identified Species: 48.57
UniProt: P61925 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61925 NP_006814.1 76 7989 S30 I H D I L V S S A S G N S N E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109785 76 7862 S30 V P D I Q G D S E A V S V R K
Dog Lupus familis XP_853601 76 7997 S30 V P D I Q G D S E A V S V R K
Cat Felis silvestris
Mouse Mus musculus Q04758 92 9663 A43 A R A G R R N A L P D I Q S S
Rat Rattus norvegicus P63249 76 7942 S30 I H D I L V S S A S G N S N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521253 76 7842 A30 V H D I L V S A A S G N P S D
Chicken Gallus gallus Q90641 76 7989 S30 L H D I L V S S P G G N S S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116417 76 7558 T30 L P D I L G S T A G P G A A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 32.8 32.8 N.A. 20.6 97.3 N.A. 72.3 81.5 N.A. 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 52.6 53.9 N.A. 38 98.6 N.A. 88.1 90.7 N.A. 63.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 20 20 N.A. 0 100 N.A. 66.6 73.3 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 46.6 46.6 N.A. 20 100 N.A. 93.3 86.6 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 0 0 0 25 50 25 0 0 13 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 88 0 0 0 25 0 0 0 13 0 0 0 25 % D
% Glu: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 38 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 38 0 0 0 25 50 13 0 0 0 % G
% His: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 0 0 88 0 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % K
% Leu: 25 0 0 0 63 0 0 0 13 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 50 0 25 0 % N
% Pro: 0 38 0 0 0 0 0 0 13 13 13 0 13 0 0 % P
% Gln: 0 0 0 0 25 0 0 0 0 0 0 0 13 0 0 % Q
% Arg: 0 13 0 0 13 13 0 0 0 0 0 0 0 25 0 % R
% Ser: 0 0 0 0 0 0 63 63 0 38 0 25 38 38 13 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % T
% Val: 38 0 0 0 0 50 0 0 0 0 25 0 25 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _