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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR5 All Species: 9.09
Human Site: S20 Identified Species: 16.67
UniProt: P61964 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61964 NP_060058.1 334 36588 S20 A R A Q P T P S S S A T Q S K
Chimpanzee Pan troglodytes Q5IS43 410 46712 G83 K E E F T S G G P L G Q K R D
Rhesus Macaque Macaca mulatta XP_001112263 330 36273 S17 R A Q L A L S S S A S Q S K E
Dog Lupus familis XP_850117 334 36428 S20 A R A Q P T P S S S A T Q S K
Cat Felis silvestris
Mouse Mus musculus Q9D7H2 328 36014 L15 A E R A Q S L L S A P R R E E
Rat Rattus norvegicus Q4V8C4 328 36030 L15 A E R A Q S P L S A P Q R V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506016 334 36605 S20 T K T Q S T P S S S T N Q S K
Chicken Gallus gallus Q9PTR5 410 46646 G83 K E E F T S G G P L G Q K R D
Frog Xenopus laevis Q90ZL4 410 46744 G83 K E E F T S G G P I G Q K R D
Zebra Danio Brachydanio rerio Q803D2 410 46511 G83 K E E I T L G G P V G Q K R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 N47 P G A T T S S N S S A S N K S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17963 376 40375 P62 P G A S A Q T P N P N A A G A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38123 315 34735
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27 84.7 96.4 N.A. 79 80.5 N.A. 97.9 27 28 28 N.A. 82.5 N.A. 61.7 N.A.
Protein Similarity: 100 45.8 90.7 97.9 N.A. 88.3 88.6 N.A. 98.1 46.5 46.3 46.5 N.A. 87.5 N.A. 74.4 N.A.
P-Site Identity: 100 0 13.3 100 N.A. 13.3 20 N.A. 60 0 0 0 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 33.3 100 N.A. 40 46.6 N.A. 66.6 13.3 13.3 6.6 N.A. 46.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 8 31 16 16 0 0 0 0 24 24 8 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 % D
% Glu: 0 47 31 0 0 0 0 0 0 0 0 0 0 8 24 % E
% Phe: 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 16 0 0 0 0 31 31 0 0 31 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 31 8 0 0 0 0 0 0 0 0 0 0 31 16 24 % K
% Leu: 0 0 0 8 0 16 8 16 0 16 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 8 8 8 0 0 % N
% Pro: 16 0 0 0 16 0 31 8 31 8 16 0 0 0 0 % P
% Gln: 0 0 8 24 16 8 0 0 0 0 0 47 24 0 0 % Q
% Arg: 8 16 16 0 0 0 0 0 0 0 0 8 16 31 0 % R
% Ser: 0 0 0 8 8 47 16 31 54 31 8 8 8 24 8 % S
% Thr: 8 0 8 8 39 24 8 0 0 0 8 16 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _