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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR5
All Species:
13.64
Human Site:
T208
Identified Species:
25
UniProt:
P61964
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61964
NP_060058.1
334
36588
T208
A
S
G
Q
C
L
K
T
L
I
D
D
D
N
P
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Rhesus Macaque
Macaca mulatta
XP_001112263
330
36273
L205
S
G
Q
C
L
K
T
L
V
D
D
D
N
P
P
Dog
Lupus familis
XP_850117
334
36428
L208
A
A
S
R
C
M
K
L
I
L
D
D
D
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
L203
S
G
Q
C
L
R
T
L
A
D
E
G
N
P
P
Rat
Rattus norvegicus
Q4V8C4
328
36030
L203
S
G
Q
C
L
R
T
L
A
D
E
G
N
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506016
334
36605
T208
A
S
G
Q
C
L
K
T
L
I
D
D
D
N
P
Chicken
Gallus gallus
Q9PTR5
410
46646
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Frog
Xenopus laevis
Q90ZL4
410
46744
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
E271
A
T
K
E
C
K
A
E
L
R
E
H
E
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
T235
A
S
G
Q
C
L
K
T
L
I
D
D
D
N
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
T250
A
N
G
Q
C
I
K
T
L
V
D
D
E
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38123
315
34735
V190
W
K
R
E
N
G
V
V
P
I
S
Q
V
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27
84.7
96.4
N.A.
79
80.5
N.A.
97.9
27
28
28
N.A.
82.5
N.A.
61.7
N.A.
Protein Similarity:
100
45.8
90.7
97.9
N.A.
88.3
88.6
N.A.
98.1
46.5
46.3
46.5
N.A.
87.5
N.A.
74.4
N.A.
P-Site Identity:
100
20
20
53.3
N.A.
6.6
6.6
N.A.
100
20
20
20
N.A.
100
N.A.
73.3
N.A.
P-Site Similarity:
100
53.3
40
86.6
N.A.
26.6
26.6
N.A.
100
53.3
53.3
53.3
N.A.
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
8
0
0
0
0
31
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
24
70
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
24
47
47
31
0
0
% D
% Glu:
0
0
0
39
0
0
0
31
0
0
47
0
39
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
24
31
0
0
8
0
0
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
31
0
31
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
31
0
0
0
0
0
% I
% Lys:
0
8
31
0
0
39
39
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
24
24
0
31
62
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
24
39
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
24
62
% P
% Gln:
0
0
24
31
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
8
0
16
0
0
0
31
0
0
0
0
0
% R
% Ser:
24
24
8
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
31
0
0
0
0
24
31
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
8
8
8
0
0
8
0
31
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _