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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR5
All Species:
6.67
Human Site:
T24
Identified Species:
12.22
UniProt:
P61964
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61964
NP_060058.1
334
36588
T24
P
T
P
S
S
S
A
T
Q
S
K
P
T
P
V
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
Q87
T
S
G
G
P
L
G
Q
K
R
D
P
K
E
W
Rhesus Macaque
Macaca mulatta
XP_001112263
330
36273
Q21
A
L
S
S
S
A
S
Q
S
K
E
V
P
K
N
Dog
Lupus familis
XP_850117
334
36428
T24
P
T
P
S
S
S
A
T
Q
S
K
P
T
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
R19
Q
S
L
L
S
A
P
R
R
E
E
E
P
Q
K
Rat
Rattus norvegicus
Q4V8C4
328
36030
Q19
Q
S
P
L
S
A
P
Q
R
V
E
E
P
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506016
334
36605
N24
S
T
P
S
S
S
T
N
Q
S
K
P
A
P
V
Chicken
Gallus gallus
Q9PTR5
410
46646
Q87
T
S
G
G
P
L
G
Q
K
R
D
P
K
E
W
Frog
Xenopus laevis
Q90ZL4
410
46744
Q87
T
S
G
G
P
I
G
Q
K
R
D
P
K
E
W
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
Q87
T
L
G
G
P
V
G
Q
K
R
D
P
K
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S51
T
S
S
N
S
S
A
S
N
K
S
S
L
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
A66
A
Q
T
P
N
P
N
A
A
G
A
S
A
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38123
315
34735
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27
84.7
96.4
N.A.
79
80.5
N.A.
97.9
27
28
28
N.A.
82.5
N.A.
61.7
N.A.
Protein Similarity:
100
45.8
90.7
97.9
N.A.
88.3
88.6
N.A.
98.1
46.5
46.3
46.5
N.A.
87.5
N.A.
74.4
N.A.
P-Site Identity:
100
6.6
13.3
100
N.A.
6.6
13.3
N.A.
73.3
6.6
6.6
6.6
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
20
33.3
100
N.A.
33.3
40
N.A.
73.3
20
20
13.3
N.A.
46.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
24
24
8
8
0
8
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
24
16
0
31
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
31
31
0
0
31
0
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
31
16
24
0
31
8
16
% K
% Leu:
0
16
8
16
0
16
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
8
8
8
0
0
0
0
0
8
% N
% Pro:
16
0
31
8
31
8
16
0
0
0
0
54
24
24
0
% P
% Gln:
16
8
0
0
0
0
0
47
24
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
0
0
0
8
16
31
0
0
0
0
0
% R
% Ser:
8
47
16
31
54
31
8
8
8
24
8
16
0
16
0
% S
% Thr:
39
24
8
0
0
0
8
16
0
0
0
0
16
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _