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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR5
All Species:
20.91
Human Site:
T290
Identified Species:
38.33
UniProt:
P61964
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61964
NP_060058.1
334
36588
T290
V
Y
I
W
N
L
Q
T
K
E
I
V
Q
K
L
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
I353
F
H
S
G
G
K
F
I
L
S
C
A
D
D
K
Rhesus Macaque
Macaca mulatta
XP_001112263
330
36273
K287
Y
I
W
N
L
Q
T
K
E
I
V
Q
K
L
Q
Dog
Lupus familis
XP_850117
334
36428
T290
V
Y
I
W
N
L
Q
T
K
E
I
V
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
K285
Y
I
W
N
L
Q
T
K
E
I
V
Q
R
L
Q
Rat
Rattus norvegicus
Q4V8C4
328
36030
K285
Y
I
W
N
L
Q
T
K
E
I
V
Q
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506016
334
36605
T290
V
Y
I
W
N
L
Q
T
K
E
I
V
Q
K
L
Chicken
Gallus gallus
Q9PTR5
410
46646
I353
F
H
S
G
G
K
F
I
L
S
C
A
D
D
K
Frog
Xenopus laevis
Q90ZL4
410
46744
I353
F
H
P
G
G
K
F
I
L
S
C
A
D
D
K
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
V353
F
H
P
G
G
R
F
V
V
S
C
A
D
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
S317
V
Y
I
W
N
L
Q
S
K
E
V
V
Q
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
T332
I
Y
I
W
N
L
Q
T
R
E
I
V
Q
C
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38123
315
34735
T272
I
Y
C
W
N
S
D
T
K
S
L
L
Q
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27
84.7
96.4
N.A.
79
80.5
N.A.
97.9
27
28
28
N.A.
82.5
N.A.
61.7
N.A.
Protein Similarity:
100
45.8
90.7
97.9
N.A.
88.3
88.6
N.A.
98.1
46.5
46.3
46.5
N.A.
87.5
N.A.
74.4
N.A.
P-Site Identity:
100
0
0
100
N.A.
0
0
N.A.
100
0
0
0
N.A.
86.6
N.A.
80
N.A.
P-Site Similarity:
100
6.6
20
100
N.A.
20
20
N.A.
100
6.6
6.6
6.6
N.A.
100
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
31
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
31
31
0
% D
% Glu:
0
0
0
0
0
0
0
0
24
39
0
0
0
0
0
% E
% Phe:
31
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
31
31
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
24
39
0
0
0
0
24
0
24
31
0
0
0
0
% I
% Lys:
0
0
0
0
0
24
0
24
39
0
0
0
8
31
31
% K
% Leu:
0
0
0
0
24
39
0
0
24
0
8
8
0
31
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
47
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
24
39
0
0
0
0
24
47
0
24
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
0
16
0
0
% R
% Ser:
0
0
16
0
0
8
0
8
0
39
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
24
39
0
0
0
0
0
0
0
% T
% Val:
31
0
0
0
0
0
0
8
8
0
31
39
0
0
0
% V
% Trp:
0
0
24
47
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _