KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1S1
All Species:
28.18
Human Site:
S147
Identified Species:
44.29
UniProt:
P61966
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61966
NP_001274.1
158
18733
S147
L
L
Q
E
E
D
E
S
P
R
S
V
L
E
E
Chimpanzee
Pan troglodytes
XP_001138231
185
21159
A175
V
L
K
A
I
E
Q
A
D
L
L
Q
E
S
F
Rhesus Macaque
Macaca mulatta
XP_001102358
160
19119
T146
L
L
Q
E
K
T
E
T
M
Y
H
S
K
S
F
Dog
Lupus familis
XP_854230
349
39164
T338
E
D
A
K
E
A
E
T
P
R
S
V
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
T149
E
D
A
K
E
A
E
T
P
R
S
V
L
E
E
Rat
Rattus norvegicus
P62744
142
16999
L132
E
T
S
Q
T
K
V
L
K
Q
L
L
M
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006261
157
18595
T146
L
L
Q
E
E
A
K
T
P
R
S
V
L
E
E
Frog
Xenopus laevis
NP_001083719
157
18689
S146
M
L
Q
E
E
D
E
S
P
R
S
V
L
E
E
Zebra Danio
Brachydanio rerio
NP_991121
157
18590
T146
M
L
Q
E
E
A
E
T
P
R
S
V
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651198
157
18555
T146
D
L
L
Q
E
D
E
T
P
Q
S
F
F
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504559
157
18615
T146
D
L
I
Q
E
E
E
T
P
Q
G
F
F
E
D
Sea Urchin
Strong. purpuratus
XP_001203214
158
18892
A147
L
L
S
E
E
L
E
A
T
R
N
A
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
A122
I
L
D
E
F
I
L
A
G
E
L
Q
E
T
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
M145
H
V
T
V
M
D
T
M
E
S
N
D
N
L
E
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
L133
E
T
S
K
Q
V
V
L
T
R
L
E
H
L
D
Conservation
Percent
Protein Identity:
100
68.6
80.6
39.2
N.A.
85
42.4
N.A.
N.A.
86
86.7
81
N.A.
76.5
N.A.
75.9
74
Protein Similarity:
100
75.6
88.7
43.5
N.A.
94.3
65.1
N.A.
N.A.
94.9
96.1
94.3
N.A.
87.9
N.A.
87.9
87.3
P-Site Identity:
100
6.6
33.3
60
N.A.
60
0
N.A.
N.A.
80
93.3
80
N.A.
40
N.A.
33.3
60
P-Site Similarity:
100
40
46.6
73.3
N.A.
73.3
33.3
N.A.
N.A.
93.3
100
93.3
N.A.
73.3
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
39.8
N.A.
N.A.
52.5
45.5
Protein Similarity:
N.A.
60.1
N.A.
N.A.
73.4
66.4
P-Site Identity:
N.A.
13.3
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
7
0
27
0
20
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
14
7
0
0
27
0
0
7
0
0
7
0
7
20
% D
% Glu:
27
0
0
47
60
14
60
0
7
7
0
7
14
54
54
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
14
14
0
14
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% H
% Ile:
7
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
20
7
7
7
0
7
0
0
0
7
0
0
% K
% Leu:
27
67
7
0
0
7
7
14
0
7
27
7
47
20
0
% L
% Met:
14
0
0
0
7
0
0
7
7
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
14
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% P
% Gln:
0
0
34
20
7
0
7
0
0
20
0
14
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% R
% Ser:
0
0
20
0
0
0
0
14
0
7
47
7
0
14
7
% S
% Thr:
0
14
7
0
7
7
7
47
14
0
0
0
0
7
0
% T
% Val:
7
7
0
7
0
7
14
0
0
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _