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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1S1
All Species:
41.21
Human Site:
Y20
Identified Species:
64.76
UniProt:
P61966
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61966
NP_001274.1
158
18733
Y20
K
L
R
L
Q
K
W
Y
L
A
T
S
D
K
E
Chimpanzee
Pan troglodytes
XP_001138231
185
21159
Y57
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Rhesus Macaque
Macaca mulatta
XP_001102358
160
19119
Y19
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Dog
Lupus familis
XP_854230
349
39164
Y208
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
Y19
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Rat
Rattus norvegicus
P62744
142
16999
L16
N
R
A
G
K
T
R
L
A
K
W
Y
M
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006261
157
18595
Y19
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Frog
Xenopus laevis
NP_001083719
157
18689
Y19
K
L
R
L
Q
K
W
Y
V
A
I
P
E
R
D
Zebra Danio
Brachydanio rerio
NP_991121
157
18590
Y19
K
L
R
L
Q
K
W
Y
V
P
L
S
D
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651198
157
18555
Y20
K
L
R
L
Q
K
W
Y
M
A
Y
P
D
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504559
157
18615
Y20
K
L
R
L
Q
K
W
Y
T
A
Y
P
D
K
Q
Sea Urchin
Strong. purpuratus
XP_001203214
158
18892
Y20
K
L
R
L
Q
K
W
Y
T
P
H
L
E
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
Y22
K
I
R
L
K
K
W
Y
T
A
M
S
A
G
E
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
A17
R
Q
G
K
T
R
L
A
K
W
Y
V
P
Y
S
Conservation
Percent
Protein Identity:
100
68.6
80.6
39.2
N.A.
85
42.4
N.A.
N.A.
86
86.7
81
N.A.
76.5
N.A.
75.9
74
Protein Similarity:
100
75.6
88.7
43.5
N.A.
94.3
65.1
N.A.
N.A.
94.9
96.1
94.3
N.A.
87.9
N.A.
87.9
87.3
P-Site Identity:
100
80
80
80
N.A.
80
0
N.A.
N.A.
80
60
66.6
N.A.
73.3
N.A.
73.3
60
P-Site Similarity:
100
86.6
86.6
86.6
N.A.
86.6
13.3
N.A.
N.A.
86.6
86.6
80
N.A.
80
N.A.
80
73.3
Percent
Protein Identity:
N.A.
39.8
N.A.
N.A.
52.5
45.5
Protein Similarity:
N.A.
60.1
N.A.
N.A.
73.4
66.4
P-Site Identity:
N.A.
0
N.A.
N.A.
60
0
P-Site Similarity:
N.A.
0
N.A.
N.A.
73.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
7
34
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
7
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
80
0
0
7
14
80
0
0
7
7
0
0
0
60
0
% K
% Leu:
0
74
0
80
0
0
7
7
7
0
40
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
7
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
47
0
20
7
0
0
% P
% Gln:
0
7
0
0
74
0
0
0
0
0
0
0
0
7
20
% Q
% Arg:
7
7
80
0
0
7
7
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
7
% S
% Thr:
0
0
0
0
7
7
0
0
20
0
7
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
47
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
80
0
0
7
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
20
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _