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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPK All Species: 28.48
Human Site: S454 Identified Species: 89.52
UniProt: P61978 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61978 NP_002131.2 463 50976 S454 A Q Y L L Q N S V K Q Y S G K
Chimpanzee Pan troglodytes XP_001155134 462 51064 S453 A Q Y L L Q N S V K Q Y S G K
Rhesus Macaque Macaca mulatta XP_001105200 462 51065 S453 A Q Y L L Q N S V K Q Y S G K
Dog Lupus familis XP_857611 463 50820 S454 A Q Y L L Q N S V K Q Y S G K
Cat Felis silvestris
Mouse Mus musculus Q61990 362 38203 S354 L I N V R L S S E T G G M G S
Rat Rattus norvegicus P61980 463 50958 S454 A Q Y L L Q N S V K Q Y S G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506808 463 50912 S454 A Q Y L L Q N S V K Q Y S G K
Chicken Gallus gallus Q5ZIQ3 427 47260 S418 A Q Y L L Q N S V K Q Y S G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 98.9 99.1 N.A. 27 100 N.A. 99.5 88.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 99.1 99.3 N.A. 42.9 100 N.A. 99.7 89.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 26.6 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 13 13 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 88 0 0 0 0 88 % K
% Leu: 13 0 0 88 88 13 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 13 0 0 0 88 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 88 0 0 0 88 0 0 0 0 88 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 13 100 0 0 0 0 88 0 13 % S
% Thr: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % T
% Val: 0 0 0 13 0 0 0 0 88 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 88 0 0 0 0 0 0 0 0 88 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _