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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP46
All Species:
53.33
Human Site:
T220
Identified Species:
78.22
UniProt:
P62068
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62068
NP_001127695.1
366
42442
T220
R
D
F
S
N
T
E
T
L
C
S
E
Q
K
Y
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
T527
R
G
F
S
N
T
E
T
L
C
S
E
Y
K
Y
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
T329
R
G
F
S
N
T
E
T
L
C
S
E
Y
K
Y
Dog
Lupus familis
XP_849650
389
45094
T243
R
D
F
S
N
T
E
T
L
C
S
E
Q
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
T224
R
G
F
S
N
T
E
T
L
C
S
E
Y
K
Y
Rat
Rattus norvegicus
XP_214034
366
42397
T220
R
D
F
S
N
T
E
T
L
C
S
E
Q
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515746
420
47812
T274
R
D
F
S
N
T
E
T
L
C
S
E
Q
K
Y
Chicken
Gallus gallus
O57429
357
40913
T215
M
D
C
L
R
L
F
T
K
E
D
V
L
D
G
Frog
Xenopus laevis
Q52KZ6
370
42846
T224
R
G
F
S
N
T
E
T
L
C
S
E
Y
K
Y
Zebra Danio
Brachydanio rerio
A5WWB0
370
42886
T224
R
D
F
S
N
T
E
T
L
C
S
E
Y
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732801
364
41625
T216
R
C
F
S
N
T
E
T
L
C
S
D
N
K
F
Honey Bee
Apis mellifera
XP_625039
354
40655
T206
R
C
F
S
N
T
E
T
L
C
S
D
N
K
F
Nematode Worm
Caenorhab. elegans
P34547
426
48259
T249
R
V
F
S
E
T
E
T
L
C
G
D
Q
K
Y
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
T218
R
G
F
S
N
T
E
T
L
C
H
E
Y
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
T219
K
N
F
S
S
T
E
T
L
H
A
E
D
K
F
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
R526
I
L
K
S
Y
H
Q
R
E
M
L
N
G
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
68
91.2
N.A.
87.3
99.7
N.A.
80.9
24.8
87.5
94.3
N.A.
72.6
74.3
60
77
Protein Similarity:
100
51.2
72.4
91.7
N.A.
92.4
100
N.A.
83.5
44.2
92.4
95.9
N.A.
82.5
83.6
72
86.6
P-Site Identity:
100
86.6
86.6
100
N.A.
86.6
100
N.A.
100
13.3
86.6
93.3
N.A.
73.3
73.3
73.3
80
P-Site Similarity:
100
86.6
86.6
100
N.A.
86.6
100
N.A.
100
13.3
86.6
93.3
N.A.
86.6
86.6
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
13
7
0
0
0
0
0
0
82
0
0
0
0
0
% C
% Asp:
0
38
0
0
0
0
0
0
0
0
7
19
7
7
0
% D
% Glu:
0
0
0
0
7
0
88
0
7
7
0
69
0
0
0
% E
% Phe:
0
0
88
0
0
0
7
0
0
0
0
0
0
0
19
% F
% Gly:
0
32
0
0
0
0
0
0
0
0
7
0
7
0
7
% G
% His:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
7
0
0
0
0
0
7
0
0
0
0
88
0
% K
% Leu:
0
7
0
7
0
7
0
0
88
0
7
0
7
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
75
0
0
0
0
0
0
7
13
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
32
0
0
% Q
% Arg:
82
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
94
7
0
0
0
0
0
69
0
0
7
0
% S
% Thr:
0
0
0
0
0
88
0
94
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
38
0
69
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _