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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CA
All Species:
21.52
Human Site:
T320
Identified Species:
31.56
UniProt:
P62136
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62136
NP_001008709.1
330
37512
T320
N
P
G
G
R
P
I
T
P
P
R
N
S
A
K
Chimpanzee
Pan troglodytes
XP_001151893
326
36742
T316
N
P
G
G
R
P
I
T
P
P
R
N
S
A
K
Rhesus Macaque
Macaca mulatta
XP_001117941
427
47327
T417
N
P
G
G
R
P
I
T
P
P
R
N
S
A
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
T320
N
P
G
G
R
P
I
T
P
P
R
N
S
A
K
Rat
Rattus norvegicus
P62138
330
37494
T320
N
P
G
G
R
P
I
T
P
P
R
N
S
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006190
323
36981
P313
A
S
R
P
V
T
P
P
R
S
M
I
T
K
Q
Frog
Xenopus laevis
Q7SZ10
323
36919
P313
A
S
R
P
V
T
P
P
R
G
I
I
T
K
Q
Zebra Danio
Brachydanio rerio
NP_997875
332
37590
P320
G
N
S
R
P
V
T
P
P
R
N
T
A
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48461
327
37351
R318
G
R
P
L
T
P
P
R
G
A
N
N
K
N
K
Honey Bee
Apis mellifera
XP_392943
329
37410
G320
R
P
V
T
P
P
R
G
G
G
N
N
K
S
K
Nematode Worm
Caenorhab. elegans
P48727
333
37773
P319
S
N
R
P
V
T
P
P
R
N
A
P
A
A
Q
Sea Urchin
Strong. purpuratus
XP_791029
330
37658
P320
S
G
R
P
V
T
P
P
R
G
T
N
N
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
T304
R
K
M
M
G
G
S
T
N
N
K
S
G
F
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48486
322
36548
T313
N
N
V
P
R
P
G
T
P
P
H
K
G
G
K
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
P303
K
P
A
Q
K
S
L
P
R
Q
A
G
G
R
K
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
K297
L
C
S
F
Q
I
L
K
P
A
E
K
K
Q
K
Conservation
Percent
Protein Identity:
100
95.1
75.1
N.A.
N.A.
99.6
100
N.A.
N.A.
90
90.3
89.7
N.A.
87.5
89.3
90.3
89.3
Protein Similarity:
100
95.4
76.8
N.A.
N.A.
100
100
N.A.
N.A.
93.3
93.3
94.8
N.A.
92.1
93
94.2
94.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
0
0
6.6
N.A.
20
26.6
6.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
13.3
13.3
13.3
N.A.
20
33.3
26.6
20
Percent
Protein Identity:
N.A.
72.4
N.A.
73.3
80.6
81.5
Protein Similarity:
N.A.
83
N.A.
85.7
87.5
88.1
P-Site Identity:
N.A.
13.3
N.A.
46.6
13.3
13.3
P-Site Similarity:
N.A.
26.6
N.A.
46.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
0
0
0
0
0
13
13
0
13
38
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
13
7
32
32
7
7
7
7
13
19
0
7
19
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
32
0
0
0
7
13
0
0
0
% I
% Lys:
7
7
0
0
7
0
0
7
0
0
7
13
19
25
69
% K
% Leu:
7
0
0
7
0
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
38
19
0
0
0
0
0
0
7
13
19
50
7
7
0
% N
% Pro:
0
44
7
32
13
50
32
38
50
38
0
7
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
7
0
0
0
7
19
% Q
% Arg:
13
7
25
7
38
0
7
7
32
7
32
0
0
7
0
% R
% Ser:
13
13
13
0
0
7
7
0
0
7
0
7
32
7
0
% S
% Thr:
0
0
0
7
7
25
7
44
0
0
7
7
13
0
0
% T
% Val:
0
0
13
0
25
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _