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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CB
All Species:
18.18
Human Site:
Y306
Identified Species:
30.77
UniProt:
P62140
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62140
NP_002700.1
327
37187
Y306
E
K
K
A
K
Y
Q
Y
G
G
L
N
S
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101758
299
34103
Y278
E
K
K
A
K
Y
Q
Y
G
G
L
N
S
G
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
G307
D
K
N
K
G
K
Y
G
Q
F
S
G
L
N
P
Rat
Rattus norvegicus
P62138
330
37494
G307
D
K
N
K
G
K
Y
G
Q
F
S
G
L
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7SZ10
323
36919
K301
Q
I
L
K
P
A
E
K
K
K
P
N
A
S
R
Zebra Danio
Brachydanio rerio
NP_001004527
327
37123
Y306
E
K
K
A
K
Y
Q
Y
S
G
V
N
S
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48462
330
37722
Y306
E
K
K
A
K
Y
L
Y
S
G
M
N
S
S
R
Honey Bee
Apis mellifera
XP_393296
328
37531
Y306
E
K
K
A
K
Y
Q
Y
L
S
L
N
T
G
Q
Nematode Worm
Caenorhab. elegans
P48727
333
37773
G306
D
K
K
K
Y
P
Y
G
A
G
G
V
G
S
N
Sea Urchin
Strong. purpuratus
XP_001175801
324
36856
Q304
S
E
K
K
A
K
Y
Q
Y
A
G
I
N
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
A296
S
F
Q
I
L
K
P
A
R
K
M
M
G
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
L299
M
M
S
V
D
E
N
L
M
C
S
F
Q
I
L
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
S291
V
D
E
S
L
L
C
S
F
Q
I
L
K
P
A
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
S288
A
M
M
S
V
D
E
S
L
L
C
S
F
Q
I
Conservation
Percent
Protein Identity:
100
N.A.
91.4
N.A.
N.A.
88.4
88.7
N.A.
N.A.
N.A.
87.7
97.2
N.A.
88.7
90.8
85.5
89.3
Protein Similarity:
100
N.A.
91.4
N.A.
N.A.
94.2
94.2
N.A.
N.A.
N.A.
92.6
98.7
N.A.
93.3
94.5
92.7
94.8
P-Site Identity:
100
N.A.
100
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
86.6
N.A.
73.3
73.3
20
6.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
33.3
93.3
N.A.
80
86.6
26.6
20
Percent
Protein Identity:
N.A.
71.5
N.A.
74.6
77.6
81.3
Protein Similarity:
N.A.
83.7
N.A.
84.4
86.5
88.3
P-Site Identity:
N.A.
6.6
N.A.
0
0
0
P-Site Similarity:
N.A.
20
N.A.
0
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
36
8
8
0
8
8
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% C
% Asp:
22
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
36
8
8
0
0
8
15
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
15
0
8
8
0
0
% F
% Gly:
0
0
0
0
15
0
0
22
15
36
15
15
15
36
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
8
8
0
8
8
% I
% Lys:
0
58
50
36
36
29
0
8
8
15
0
0
8
0
0
% K
% Leu:
0
0
8
0
15
8
8
8
15
8
22
8
15
0
8
% L
% Met:
8
15
8
0
0
0
0
0
8
0
15
8
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
0
0
43
8
15
8
% N
% Pro:
0
0
0
0
8
8
8
0
0
0
8
0
0
8
15
% P
% Gln:
8
0
8
0
0
0
29
8
15
8
0
0
8
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
36
% R
% Ser:
15
0
8
15
0
0
0
15
15
8
22
8
29
29
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
8
8
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
36
29
36
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _