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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCS1 All Species: 36.97
Human Site: S178 Identified Species: 73.94
UniProt: P62166 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62166 NP_001122298.1 190 21879 S178 E G S K A D P S I V Q A L S L
Chimpanzee Pan troglodytes XP_001165534 173 19721 K162 R I F A M M D K M P G N H S P
Rhesus Macaque Macaca mulatta XP_001118646 208 23771 S196 E G S K A D P S I V Q A L S L
Dog Lupus familis XP_548415 254 28291 S242 E G S K A D P S I V Q A L S L
Cat Felis silvestris
Mouse Mus musculus Q8BNY6 190 21860 S178 E G S K A D P S I V Q A L S L
Rat Rattus norvegicus P62749 193 22320 S178 K G A K S D P S I V R L L Q C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P42324 193 22251 S178 K G A K S D P S I V R L L Q C
Frog Xenopus laevis Q91614 190 21906 S178 E G S K A D P S I V Q A L S L
Zebra Danio Brachydanio rerio Q6AXL4 192 21965 S178 E G A K N D P S I V R L L Q C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37236 187 21650 D175 F R E G S K A D P R I V Q A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P36608 191 22003 S178 E G A K A D P S I V H A L S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06389 190 21992 S178 E G S K V D P S I I G A L N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 84.6 66.5 N.A. 100 58 N.A. N.A. 58 98.9 58.8 N.A. 70.5 N.A. 74.8 N.A.
Protein Similarity: 100 78.9 87 70.8 N.A. 100 76.1 N.A. N.A. 75.6 99.4 75 N.A. 82.6 N.A. 86.9 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 53.3 N.A. N.A. 53.3 100 60 N.A. 6.6 N.A. 86.6 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 80 N.A. N.A. 80 100 73.3 N.A. 20 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 60 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 75.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 34 9 50 0 9 0 0 0 0 59 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % C
% Asp: 0 0 0 0 0 84 9 9 0 0 0 0 0 0 0 % D
% Glu: 67 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 84 0 9 0 0 0 0 0 0 17 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 84 9 9 0 0 0 0 % I
% Lys: 17 0 0 84 0 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 25 84 0 67 % L
% Met: 0 0 0 0 9 9 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 9 0 9 0 % N
% Pro: 0 0 0 0 0 0 84 0 9 9 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 42 0 9 25 0 % Q
% Arg: 9 9 0 0 0 0 0 0 0 9 25 0 0 0 0 % R
% Ser: 0 0 50 0 25 0 0 84 0 0 0 0 0 59 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 75 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _