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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCS1
All Species:
36.97
Human Site:
S178
Identified Species:
73.94
UniProt:
P62166
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62166
NP_001122298.1
190
21879
S178
E
G
S
K
A
D
P
S
I
V
Q
A
L
S
L
Chimpanzee
Pan troglodytes
XP_001165534
173
19721
K162
R
I
F
A
M
M
D
K
M
P
G
N
H
S
P
Rhesus Macaque
Macaca mulatta
XP_001118646
208
23771
S196
E
G
S
K
A
D
P
S
I
V
Q
A
L
S
L
Dog
Lupus familis
XP_548415
254
28291
S242
E
G
S
K
A
D
P
S
I
V
Q
A
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNY6
190
21860
S178
E
G
S
K
A
D
P
S
I
V
Q
A
L
S
L
Rat
Rattus norvegicus
P62749
193
22320
S178
K
G
A
K
S
D
P
S
I
V
R
L
L
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P42324
193
22251
S178
K
G
A
K
S
D
P
S
I
V
R
L
L
Q
C
Frog
Xenopus laevis
Q91614
190
21906
S178
E
G
S
K
A
D
P
S
I
V
Q
A
L
S
L
Zebra Danio
Brachydanio rerio
Q6AXL4
192
21965
S178
E
G
A
K
N
D
P
S
I
V
R
L
L
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37236
187
21650
D175
F
R
E
G
S
K
A
D
P
R
I
V
Q
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36608
191
22003
S178
E
G
A
K
A
D
P
S
I
V
H
A
L
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06389
190
21992
S178
E
G
S
K
V
D
P
S
I
I
G
A
L
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
84.6
66.5
N.A.
100
58
N.A.
N.A.
58
98.9
58.8
N.A.
70.5
N.A.
74.8
N.A.
Protein Similarity:
100
78.9
87
70.8
N.A.
100
76.1
N.A.
N.A.
75.6
99.4
75
N.A.
82.6
N.A.
86.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
53.3
N.A.
N.A.
53.3
100
60
N.A.
6.6
N.A.
86.6
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
80
N.A.
N.A.
80
100
73.3
N.A.
20
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
9
50
0
9
0
0
0
0
59
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% C
% Asp:
0
0
0
0
0
84
9
9
0
0
0
0
0
0
0
% D
% Glu:
67
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
84
0
9
0
0
0
0
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
84
9
9
0
0
0
0
% I
% Lys:
17
0
0
84
0
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
25
84
0
67
% L
% Met:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
84
0
9
9
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
42
0
9
25
0
% Q
% Arg:
9
9
0
0
0
0
0
0
0
9
25
0
0
0
0
% R
% Ser:
0
0
50
0
25
0
0
84
0
0
0
0
0
59
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
75
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _