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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCS1 All Species: 29.39
Human Site: T23 Identified Species: 58.79
UniProt: P62166 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62166 NP_001122298.1 190 21879 T23 L T R K T Y F T E K E V Q Q W
Chimpanzee Pan troglodytes XP_001165534 173 19721 L15 P K A P P S I L V L R K P K G
Rhesus Macaque Macaca mulatta XP_001118646 208 23771 T41 L T T E R E F T E K E V Q Q W
Dog Lupus familis XP_548415 254 28291 V87 R R G S V E K V G E A E C L M
Cat Felis silvestris
Mouse Mus musculus Q8BNY6 190 21860 T23 L T R K T Y F T E K E V Q Q W
Rat Rattus norvegicus P62749 193 22320 T23 L R E H T E F T D H E L Q E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P42324 193 22251 T23 L R E N T E F T D H E L Q E W
Frog Xenopus laevis Q91614 190 21906 T23 L T R K T Y F T E K E V Q Q W
Zebra Danio Brachydanio rerio Q6AXL4 192 21965 T23 L L D N T D F T E H E I L E W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37236 187 21650 T23 L T T D T Y F T E K E I R Q W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P36608 191 22003 T23 L A E Q T Y F T E K E I K Q W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06389 190 21992 D23 L K Q S T Y F D R R E I Q Q W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 84.6 66.5 N.A. 100 58 N.A. N.A. 58 98.9 58.8 N.A. 70.5 N.A. 74.8 N.A.
Protein Similarity: 100 78.9 87 70.8 N.A. 100 76.1 N.A. N.A. 75.6 99.4 75 N.A. 82.6 N.A. 86.9 N.A.
P-Site Identity: 100 0 73.3 0 N.A. 100 46.6 N.A. N.A. 46.6 100 46.6 N.A. 73.3 N.A. 66.6 N.A.
P-Site Similarity: 100 6.6 80 6.6 N.A. 100 66.6 N.A. N.A. 66.6 100 60 N.A. 86.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 60 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 75.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 9 9 0 9 0 9 17 0 0 0 0 0 0 % D
% Glu: 0 0 25 9 0 34 0 0 59 9 84 9 0 25 0 % E
% Phe: 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 9 % G
% His: 0 0 0 9 0 0 0 0 0 25 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 34 0 0 0 % I
% Lys: 0 17 0 25 0 0 9 0 0 50 0 9 9 9 0 % K
% Leu: 84 9 0 0 0 0 0 9 0 9 0 17 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 9 9 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 9 9 0 0 0 0 0 0 0 0 59 59 0 % Q
% Arg: 9 25 25 0 9 0 0 0 9 9 9 0 9 0 0 % R
% Ser: 0 0 0 17 0 9 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 42 17 0 75 0 0 75 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 9 9 0 0 34 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 % W
% Tyr: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _