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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCS1
All Species:
19.09
Human Site:
Y21
Identified Species:
38.18
UniProt:
P62166
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62166
NP_001122298.1
190
21879
Y21
E
E
L
T
R
K
T
Y
F
T
E
K
E
V
Q
Chimpanzee
Pan troglodytes
XP_001165534
173
19721
S13
P
G
P
K
A
P
P
S
I
L
V
L
R
K
P
Rhesus Macaque
Macaca mulatta
XP_001118646
208
23771
E39
P
G
L
T
T
E
R
E
F
T
E
K
E
V
Q
Dog
Lupus familis
XP_548415
254
28291
E85
G
A
R
R
G
S
V
E
K
V
G
E
A
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNY6
190
21860
Y21
E
E
L
T
R
K
T
Y
F
T
E
K
E
V
Q
Rat
Rattus norvegicus
P62749
193
22320
E21
Q
D
L
R
E
H
T
E
F
T
D
H
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P42324
193
22251
E21
Q
D
L
R
E
N
T
E
F
T
D
H
E
L
Q
Frog
Xenopus laevis
Q91614
190
21906
Y21
E
E
L
T
R
K
T
Y
F
T
E
K
E
V
Q
Zebra Danio
Brachydanio rerio
Q6AXL4
192
21965
D21
Q
D
L
L
D
N
T
D
F
T
E
H
E
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37236
187
21650
Y21
D
R
L
T
T
D
T
Y
F
T
E
K
E
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36608
191
22003
Y21
R
D
L
A
E
Q
T
Y
F
T
E
K
E
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06389
190
21992
Y21
T
C
L
K
Q
S
T
Y
F
D
R
R
E
I
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
84.6
66.5
N.A.
100
58
N.A.
N.A.
58
98.9
58.8
N.A.
70.5
N.A.
74.8
N.A.
Protein Similarity:
100
78.9
87
70.8
N.A.
100
76.1
N.A.
N.A.
75.6
99.4
75
N.A.
82.6
N.A.
86.9
N.A.
P-Site Identity:
100
0
60
0
N.A.
100
40
N.A.
N.A.
40
100
40
N.A.
60
N.A.
53.3
N.A.
P-Site Similarity:
100
0
66.6
6.6
N.A.
100
66.6
N.A.
N.A.
66.6
100
60
N.A.
80
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
34
0
0
9
9
0
9
0
9
17
0
0
0
0
% D
% Glu:
25
25
0
0
25
9
0
34
0
0
59
9
84
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% F
% Gly:
9
17
0
0
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
25
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
34
0
% I
% Lys:
0
0
0
17
0
25
0
0
9
0
0
50
0
9
9
% K
% Leu:
0
0
84
9
0
0
0
0
0
9
0
9
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
9
0
0
9
9
0
0
0
0
0
0
0
9
% P
% Gln:
25
0
0
0
9
9
0
0
0
0
0
0
0
0
59
% Q
% Arg:
9
9
9
25
25
0
9
0
0
0
9
9
9
0
9
% R
% Ser:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
42
17
0
75
0
0
75
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
9
9
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _