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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC1 All Species: 50
Human Site: T53 Identified Species: 64.71
UniProt: P62191 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62191 NP_002793.2 440 49185 T53 A S K L P L V T P H T Q C R L
Chimpanzee Pan troglodytes XP_001142567 399 44420 K41 G K K K K K T K G P D A A S K
Rhesus Macaque Macaca mulatta XP_001103312 440 49180 T53 A S K L P L V T P H T Q C R L
Dog Lupus familis XP_848524 440 49333 T53 A S K L P L V T P H T Q C R L
Cat Felis silvestris
Mouse Mus musculus P54775 418 47263 Q49 S R Y K K L Q Q E L E F L E V
Rat Rattus norvegicus P62193 440 49166 T53 A S K L P L V T P H T Q C R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517805 388 43713 Q32 E F I R N Q E Q M K P L E E K
Chicken Gallus gallus Q90732 440 49185 T53 A S K P P L V T P H T Q C R L
Frog Xenopus laevis P46470 461 52229 E56 A K V R L L R E E L Q L L Q E
Zebra Danio Brachydanio rerio NP_001002091 440 49193 T53 A S K L P L V T P H T Q C R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 T52 A M K L P Q V T P H T R C R L
Honey Bee Apis mellifera XP_623527 440 49215 T53 A L K L P Q V T P H T R C R L
Nematode Worm Caenorhab. elegans O16368 443 49704 T56 A S K L P A V T P H A R C R L
Sea Urchin Strong. purpuratus XP_796230 443 49683 T56 A S K L P Q V T P H T K C R L
Poplar Tree Populus trichocarpa XP_002301829 446 49676 T59 A A R L P T V T P H T K C K L
Maize Zea mays NP_001146268 446 49429 A59 A A R L P A V A P L S K C R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL67 443 49328 T56 A A R L P T V T P S T K C K L
Baker's Yeast Sacchar. cerevisiae P40327 437 48810 Y50 A E K L P N I Y P S T R C K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 99.7 97 N.A. 45 100 N.A. 88.1 98.6 42.2 97.2 N.A. 91.3 91.8 83 89.6
Protein Similarity: 100 90.4 100 98.1 N.A. 68.1 100 N.A. 88.1 99 60 99.5 N.A. 95.9 96.3 92.7 95.2
P-Site Identity: 100 6.6 100 100 N.A. 6.6 100 N.A. 0 93.3 13.3 100 N.A. 80 80 80 86.6
P-Site Similarity: 100 6.6 100 100 N.A. 20 100 N.A. 0 93.3 20 100 N.A. 86.6 86.6 86.6 93.3
Percent
Protein Identity: 77.3 76 N.A. 77.4 71.3 N.A.
Protein Similarity: 90.5 90.3 N.A. 90.5 85.6 N.A.
P-Site Identity: 66.6 53.3 N.A. 60 53.3 N.A.
P-Site Similarity: 93.3 80 N.A. 86.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 17 0 0 0 12 0 6 0 0 6 6 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % D
% Glu: 6 6 0 0 0 0 6 6 12 0 6 0 6 12 6 % E
% Phe: 0 6 0 0 0 0 0 0 0 0 0 6 0 0 0 % F
% Gly: 6 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 % H
% Ile: 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 67 12 12 6 0 6 0 6 0 23 0 17 12 % K
% Leu: 0 6 0 73 6 45 0 0 0 17 0 12 12 0 78 % L
% Met: 0 6 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 6 78 0 0 0 78 6 6 0 0 0 0 % P
% Gln: 0 0 0 0 0 23 6 12 0 0 6 34 0 6 0 % Q
% Arg: 0 6 17 12 0 0 6 0 0 0 0 23 0 62 0 % R
% Ser: 6 45 0 0 0 0 0 0 0 12 6 0 0 6 0 % S
% Thr: 0 0 0 0 0 12 6 67 0 0 67 0 0 0 0 % T
% Val: 0 0 6 0 0 0 73 0 0 0 0 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _