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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC1 All Species: 56.06
Human Site: Y132 Identified Species: 72.55
UniProt: P62191 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62191 NP_002793.2 440 49185 Y132 T S V G S E H Y V S I L S F V
Chimpanzee Pan troglodytes XP_001142567 399 44420 V109 L R G T P M S V G T L E E I I
Rhesus Macaque Macaca mulatta XP_001103312 440 49180 Y132 T S V G S E H Y I S I L S F V
Dog Lupus familis XP_848524 440 49333 Y132 T S V G S E H Y V S I L S F V
Cat Felis silvestris
Mouse Mus musculus P54775 418 47263 S117 N Y Y V R M V S T I D R E L L
Rat Rattus norvegicus P62193 440 49166 Y132 T S V G S E H Y V S I L S F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517805 388 43713 L100 E P G C S V L L N H K V H A V
Chicken Gallus gallus Q90732 440 49185 Y132 T S V G S E H Y V S I L S F V
Frog Xenopus laevis P46470 461 52229 K125 L H K I L P N K V D P L V S L
Zebra Danio Brachydanio rerio NP_001002091 440 49193 Y132 T S V G S E H Y V S I L S F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 Y131 T S V G S E H Y V S I L S F V
Honey Bee Apis mellifera XP_623527 440 49215 Y132 T S V G S E H Y V S I L S F V
Nematode Worm Caenorhab. elegans O16368 443 49704 Y135 T N V G S E H Y V N I M S F V
Sea Urchin Strong. purpuratus XP_796230 443 49683 Y135 A S V G S E Y Y V S I L S F V
Poplar Tree Populus trichocarpa XP_002301829 446 49676 Y138 S S V G P E Y Y V G I L S F V
Maize Zea mays NP_001146268 446 49429 Y138 S S V G P E Y Y V G I L S F V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL67 443 49328 Y135 S S V G P E Y Y V G I L S F V
Baker's Yeast Sacchar. cerevisiae P40327 437 48810 Y129 S P T M P D Y Y V S I L S F V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 99.7 97 N.A. 45 100 N.A. 88.1 98.6 42.2 97.2 N.A. 91.3 91.8 83 89.6
Protein Similarity: 100 90.4 100 98.1 N.A. 68.1 100 N.A. 88.1 99 60 99.5 N.A. 95.9 96.3 92.7 95.2
P-Site Identity: 100 0 93.3 100 N.A. 0 100 N.A. 13.3 100 13.3 100 N.A. 100 100 80 86.6
P-Site Similarity: 100 20 100 100 N.A. 6.6 100 N.A. 20 100 26.6 100 N.A. 100 100 100 93.3
Percent
Protein Identity: 77.3 76 N.A. 77.4 71.3 N.A.
Protein Similarity: 90.5 90.3 N.A. 90.5 85.6 N.A.
P-Site Identity: 73.3 73.3 N.A. 73.3 53.3 N.A.
P-Site Similarity: 86.6 86.6 N.A. 86.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % A
% Cys: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 0 0 0 6 6 0 0 0 0 % D
% Glu: 6 0 0 0 0 73 0 0 0 0 0 6 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 78 0 % F
% Gly: 0 0 12 73 0 0 0 0 6 17 0 0 0 0 0 % G
% His: 0 6 0 0 0 0 50 0 0 6 0 0 6 0 0 % H
% Ile: 0 0 0 6 0 0 0 0 6 6 78 0 0 6 6 % I
% Lys: 0 0 6 0 0 0 0 6 0 0 6 0 0 0 0 % K
% Leu: 12 0 0 0 6 0 6 6 0 0 6 78 0 6 12 % L
% Met: 0 0 0 6 0 12 0 0 0 0 0 6 0 0 0 % M
% Asn: 6 6 0 0 0 0 6 0 6 6 0 0 0 0 0 % N
% Pro: 0 12 0 0 28 6 0 0 0 0 6 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 6 0 0 6 0 0 0 0 0 0 6 0 0 0 % R
% Ser: 23 67 0 0 62 0 6 6 0 56 0 0 78 6 0 % S
% Thr: 50 0 6 6 0 0 0 0 6 6 0 0 0 0 0 % T
% Val: 0 0 73 6 0 6 6 6 78 0 0 6 6 0 84 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 6 0 0 0 28 78 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _