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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC1
All Species:
59.09
Human Site:
Y295
Identified Species:
76.47
UniProt:
P62191
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62191
NP_002793.2
440
49185
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Chimpanzee
Pan troglodytes
XP_001142567
399
44420
G263
I
Q
K
Y
L
G
D
G
P
K
L
V
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001103312
440
49180
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Dog
Lupus familis
XP_848524
440
49333
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
F275
D
A
I
A
T
K
R
F
D
A
Q
T
G
A
D
Rat
Rattus norvegicus
P62193
440
49166
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517805
388
43713
I253
N
S
G
G
E
R
E
I
Q
R
T
M
L
E
L
Chicken
Gallus gallus
Q90732
440
49185
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Frog
Xenopus laevis
P46470
461
52229
I292
V
I
M
A
T
N
R
I
D
I
L
D
S
A
L
Zebra Danio
Brachydanio rerio
NP_001002091
440
49193
Y295
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
Y294
D
A
V
G
T
K
R
Y
D
S
N
S
G
G
E
Honey Bee
Apis mellifera
XP_623527
440
49215
Y295
D
A
V
G
T
K
R
Y
D
S
N
S
G
G
E
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y298
D
A
V
G
T
K
R
Y
D
S
N
S
G
G
E
Sea Urchin
Strong. purpuratus
XP_796230
443
49683
Y298
D
A
I
G
T
K
R
Y
E
S
N
S
G
G
E
Poplar Tree
Populus trichocarpa
XP_002301829
446
49676
Y301
D
A
V
G
T
K
R
Y
D
A
H
S
G
G
E
Maize
Zea mays
NP_001146268
446
49429
Y301
D
A
V
G
T
K
R
Y
D
A
H
S
G
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL67
443
49328
Y298
D
A
V
G
T
K
R
Y
D
A
N
S
G
G
E
Baker's Yeast
Sacchar. cerevisiae
P40327
437
48810
Y292
D
A
I
G
T
K
R
Y
D
S
N
S
G
G
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.7
97
N.A.
45
100
N.A.
88.1
98.6
42.2
97.2
N.A.
91.3
91.8
83
89.6
Protein Similarity:
100
90.4
100
98.1
N.A.
68.1
100
N.A.
88.1
99
60
99.5
N.A.
95.9
96.3
92.7
95.2
P-Site Identity:
100
0
100
100
N.A.
53.3
100
N.A.
6.6
100
20
100
N.A.
93.3
93.3
93.3
93.3
P-Site Similarity:
100
0
100
100
N.A.
80
100
N.A.
26.6
100
26.6
100
N.A.
100
100
100
100
Percent
Protein Identity:
77.3
76
N.A.
77.4
71.3
N.A.
Protein Similarity:
90.5
90.3
N.A.
90.5
85.6
N.A.
P-Site Identity:
80
80
N.A.
86.6
100
N.A.
P-Site Similarity:
100
100
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
84
0
12
0
0
0
0
0
23
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
84
0
0
0
0
0
6
0
84
0
0
6
0
0
6
% D
% Glu:
0
0
0
0
6
0
6
0
6
0
0
0
0
12
78
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
6
84
0
6
0
6
0
0
0
0
84
78
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
6
6
50
0
0
0
0
12
0
6
0
0
0
0
0
% I
% Lys:
0
0
6
0
0
84
0
0
0
6
0
0
0
0
0
% K
% Leu:
0
0
0
0
6
0
0
0
0
0
12
0
6
0
17
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
6
0
0
0
0
6
0
0
0
0
67
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% P
% Gln:
0
6
0
0
0
0
0
0
6
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
89
0
0
6
0
0
6
0
0
% R
% Ser:
0
6
0
0
0
0
0
0
0
62
0
78
6
0
0
% S
% Thr:
0
0
0
0
89
0
0
0
0
0
6
6
0
0
0
% T
% Val:
6
0
34
0
0
0
0
0
0
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _