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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC5
All Species:
33.03
Human Site:
S257
Identified Species:
55.9
UniProt:
P62195
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62195
NP_002796.4
406
45626
S257
E
I
D
S
I
G
S
S
R
L
E
G
G
S
G
Chimpanzee
Pan troglodytes
XP_001149845
406
45725
S257
E
I
D
S
I
G
S
S
R
L
E
G
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001108909
477
53189
S328
E
I
D
S
I
G
S
S
R
L
E
G
G
S
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46471
433
48629
A283
E
I
D
A
I
G
G
A
R
F
D
D
G
A
G
Rat
Rattus norvegicus
P62193
440
49166
K293
E
I
D
A
I
G
T
K
R
Y
D
S
N
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90732
440
49185
K293
E
I
D
A
I
G
T
K
R
Y
D
S
N
S
G
Frog
Xenopus laevis
P46470
461
52229
S251
D
E
I
D
S
I
G
S
R
L
E
G
G
S
G
Zebra Danio
Brachydanio rerio
NP_001003740
406
45613
S257
E
I
D
S
I
G
S
S
R
L
E
G
G
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18413
405
45839
S256
E
I
D
S
I
G
S
S
R
I
E
S
G
S
G
Honey Bee
Apis mellifera
XP_623053
405
45745
S256
E
I
D
S
I
G
S
S
R
I
E
S
G
S
G
Nematode Worm
Caenorhab. elegans
O16368
443
49704
K296
E
I
D
A
V
G
T
K
R
Y
D
S
N
S
G
Sea Urchin
Strong. purpuratus
XP_784151
401
45350
T252
E
I
D
S
I
G
S
T
R
I
E
G
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5U3
419
47229
R270
I
D
S
I
G
S
A
R
M
E
S
G
S
G
N
Baker's Yeast
Sacchar. cerevisiae
Q01939
405
45253
T256
E
I
D
S
I
G
S
T
R
V
E
G
S
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
84.9
N.A.
N.A.
44.7
42.7
N.A.
N.A.
42
84.8
98
N.A.
91.8
91.6
41.5
89.9
Protein Similarity:
100
98.7
84.9
N.A.
N.A.
62.3
61.1
N.A.
N.A.
60.2
86.1
99
N.A.
95.5
95.8
62
96.3
P-Site Identity:
100
100
100
N.A.
N.A.
53.3
53.3
N.A.
N.A.
53.3
53.3
100
N.A.
86.6
86.6
46.6
80
P-Site Similarity:
100
100
100
N.A.
N.A.
80
73.3
N.A.
N.A.
73.3
60
100
N.A.
93.3
93.3
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
79.7
73.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
88.5
86.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
29
0
0
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
86
8
0
0
0
0
0
0
29
8
0
0
0
% D
% Glu:
86
8
0
0
0
0
0
0
0
8
65
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
86
15
0
0
0
0
58
58
15
93
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
86
8
8
79
8
0
0
0
22
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
93
0
0
0
0
0
0
% R
% Ser:
0
0
8
58
8
8
58
50
0
0
8
36
22
79
0
% S
% Thr:
0
0
0
0
0
0
22
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _