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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC5 All Species: 39.7
Human Site: S263 Identified Species: 67.18
UniProt: P62195 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62195 NP_002796.4 406 45626 S263 S S R L E G G S G G D S E V Q
Chimpanzee Pan troglodytes XP_001149845 406 45725 S263 S S R L E G G S G G D S E V Q
Rhesus Macaque Macaca mulatta XP_001108909 477 53189 S334 S S R L E G G S G G D S E V Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 A289 G A R F D D G A G G D N E V Q
Rat Rattus norvegicus P62193 440 49166 S299 T K R Y D S N S G G E R E I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 S299 T K R Y D S N S G G E R E I Q
Frog Xenopus laevis P46470 461 52229 S257 G S R L E G G S G G D S E V Q
Zebra Danio Brachydanio rerio NP_001003740 406 45613 S263 S S R L E G G S G G D S E V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 S262 S S R I E S G S G G D S E V Q
Honey Bee Apis mellifera XP_623053 405 45745 S262 S S R I E S G S G G D S E V Q
Nematode Worm Caenorhab. elegans O16368 443 49704 S302 T K R Y D S N S G G E R E I Q
Sea Urchin Strong. purpuratus XP_784151 401 45350 S258 S T R I E G S S G G D S E V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5U3 419 47229 G276 A R M E S G S G N G D S E V Q
Baker's Yeast Sacchar. cerevisiae Q01939 405 45253 G262 S T R V E G S G G G D S E V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.9 N.A. N.A. 44.7 42.7 N.A. N.A. 42 84.8 98 N.A. 91.8 91.6 41.5 89.9
Protein Similarity: 100 98.7 84.9 N.A. N.A. 62.3 61.1 N.A. N.A. 60.2 86.1 99 N.A. 95.5 95.8 62 96.3
P-Site Identity: 100 100 100 N.A. N.A. 53.3 40 N.A. N.A. 40 93.3 100 N.A. 86.6 86.6 40 80
P-Site Similarity: 100 100 100 N.A. N.A. 80 66.6 N.A. N.A. 66.6 93.3 100 N.A. 93.3 93.3 66.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 79.7 73.8 N.A.
Protein Similarity: N.A. N.A. N.A. 88.5 86.2 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 29 8 0 0 0 0 79 0 0 0 0 % D
% Glu: 0 0 0 8 65 0 0 0 0 0 22 0 100 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 58 58 15 93 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 22 0 0 0 0 0 0 0 0 0 22 0 % I
% Lys: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 22 0 8 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % Q
% Arg: 0 8 93 0 0 0 0 0 0 0 0 22 0 0 0 % R
% Ser: 58 50 0 0 8 36 22 79 0 0 0 72 0 0 0 % S
% Thr: 22 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 79 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _