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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC5 All Species: 32.73
Human Site: S39 Identified Species: 55.38
UniProt: P62195 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62195 NP_002796.4 406 45626 S39 Q L I V N D K S Q N L R R L Q
Chimpanzee Pan troglodytes XP_001149845 406 45725 S39 Q L I V N D K S Q N L R R L Q
Rhesus Macaque Macaca mulatta XP_001108909 477 53189 S110 Q L I V N D K S Q N L R R L Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 Q53 K Q V E D D I Q Q L L K K I N
Rat Rattus norvegicus P62193 440 49166 I79 L L M E E E F I R N Q E Q M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 I79 L L M E E E F I R N Q E Q M K
Frog Xenopus laevis P46470 461 52229 S34 Q L V V N D K S Q N L R R L Q
Zebra Danio Brachydanio rerio NP_001003740 406 45613 S39 Q L T V N E K S Q N L R R L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 H38 Q L V V A E K H Q N L R R L Q
Honey Bee Apis mellifera XP_623053 405 45745 S38 Q L I V A E K S Q N L R R L Q
Nematode Worm Caenorhab. elegans O16368 443 49704 I71 K L L K S E R I K D Y L L M E
Sea Urchin Strong. purpuratus XP_784151 401 45350 T34 Q M V V T D K T Q N L R R L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5U3 419 47229 T51 Q R Q L R Q K T N N L N R L E
Baker's Yeast Sacchar. cerevisiae Q01939 405 45253 T38 E L K I R S K T E N V R R L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.9 N.A. N.A. 44.7 42.7 N.A. N.A. 42 84.8 98 N.A. 91.8 91.6 41.5 89.9
Protein Similarity: 100 98.7 84.9 N.A. N.A. 62.3 61.1 N.A. N.A. 60.2 86.1 99 N.A. 95.5 95.8 62 96.3
P-Site Identity: 100 100 100 N.A. N.A. 20 13.3 N.A. N.A. 13.3 93.3 86.6 N.A. 73.3 86.6 6.6 66.6
P-Site Similarity: 100 100 100 N.A. N.A. 60 53.3 N.A. N.A. 53.3 100 93.3 N.A. 86.6 93.3 66.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 79.7 73.8 N.A.
Protein Similarity: N.A. N.A. N.A. 88.5 86.2 N.A.
P-Site Identity: N.A. N.A. N.A. 40 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 43 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 22 15 43 0 0 8 0 0 15 0 0 29 % E
% Phe: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 29 8 0 0 8 22 0 0 0 0 0 8 0 % I
% Lys: 15 0 8 8 0 0 72 0 8 0 0 8 8 0 15 % K
% Leu: 15 79 8 8 0 0 0 0 0 8 72 8 8 72 0 % L
% Met: 0 8 15 0 0 0 0 0 0 0 0 0 0 22 0 % M
% Asn: 0 0 0 0 36 0 0 0 8 86 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 65 8 8 0 0 8 0 8 65 0 15 0 15 0 50 % Q
% Arg: 0 8 0 0 15 0 8 0 15 0 0 65 72 0 0 % R
% Ser: 0 0 0 0 8 8 0 43 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 8 0 0 22 0 0 0 0 0 0 0 % T
% Val: 0 0 29 58 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _