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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC5 All Species: 54.55
Human Site: T379 Identified Species: 92.31
UniProt: P62195 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62195 NP_002796.4 406 45626 T379 R E R R V H V T Q E D F E M A
Chimpanzee Pan troglodytes XP_001149845 406 45725 T379 R E R R V H V T Q E D F E M A
Rhesus Macaque Macaca mulatta XP_001108909 477 53189 T450 R E R R V H V T Q E D F E M A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 T405 R A R R K I A T E K D F L E A
Rat Rattus norvegicus P62193 440 49166 T415 R E R R M K V T N E D F K K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 T415 R E R R M K V T N E D F K K S
Frog Xenopus laevis P46470 461 52229 T373 R E R R V H V T Q E D F E M A
Zebra Danio Brachydanio rerio NP_001003740 406 45613 T379 R E R R V H V T Q E D F E M A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 T378 R E R R V H V T Q E D F E M A
Honey Bee Apis mellifera XP_623053 405 45745 T378 R E R R V H V T Q E D F E M A
Nematode Worm Caenorhab. elegans O16368 443 49704 T418 R E R R M R V T M E D F Q K S
Sea Urchin Strong. purpuratus XP_784151 401 45350 T374 R E R R V H V T Q E D F E M A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5U3 419 47229 T392 R E R R V H V T Q E D F E M A
Baker's Yeast Sacchar. cerevisiae Q01939 405 45253 T378 R E R R I H V T Q E D F E L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.9 N.A. N.A. 44.7 42.7 N.A. N.A. 42 84.8 98 N.A. 91.8 91.6 41.5 89.9
Protein Similarity: 100 98.7 84.9 N.A. N.A. 62.3 61.1 N.A. N.A. 60.2 86.1 99 N.A. 95.5 95.8 62 96.3
P-Site Identity: 100 100 100 N.A. N.A. 46.6 60 N.A. N.A. 60 100 100 N.A. 100 100 60 100
P-Site Similarity: 100 100 100 N.A. N.A. 60 80 N.A. N.A. 80 100 100 N.A. 100 100 80 100
Percent
Protein Identity: N.A. N.A. N.A. 79.7 73.8 N.A.
Protein Similarity: N.A. N.A. N.A. 88.5 86.2 N.A.
P-Site Identity: N.A. N.A. N.A. 100 86.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 79 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % D
% Glu: 0 93 0 0 0 0 0 0 8 93 0 0 72 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 72 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 15 0 0 0 8 0 0 15 22 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 22 0 0 0 8 0 0 0 0 65 0 % M
% Asn: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 72 0 0 0 8 0 0 % Q
% Arg: 100 0 100 100 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % S
% Thr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 65 0 93 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _