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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2H All Species: 25.45
Human Site: T44 Identified Species: 43.08
UniProt: P62256 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62256 NP_003335.1 183 20655 T44 K F Y G P Q G T P Y E G G V W
Chimpanzee Pan troglodytes XP_001144807 281 31534 T142 K F Y G P Q G T P Y E G G V W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_857373 142 16071
Cat Felis silvestris
Mouse Mus musculus Q9Z255 152 17297 K14 R R L M R D F K R L Q E D P P
Rat Rattus norvegicus P63149 152 17294 K14 R R L M R D F K R L Q E D P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510166 373 41462 T234 K F Y G P Q G T P Y E G G V W
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958897 183 20649 T44 K F Y G P Q G T P Y E G G V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35128 151 17217 R14 R I I K E T Q R L M Q E P V P
Honey Bee Apis mellifera XP_395791 187 21061 T44 K F Y G P R G T P Y E G G I W
Nematode Worm Caenorhab. elegans P52478 192 21494 T46 I I F G P Q E T P F E D G T F
Sea Urchin Strong. purpuratus XP_783798 181 20592 T44 K F Y G P K G T A Y E G G V W
Poplar Tree Populus trichocarpa XP_002321579 186 21163 G47 K E S L Y E G G V W K I H V E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42749 185 21160 Y44 S G P K D S I Y E G G V W K I
Baker's Yeast Sacchar. cerevisiae P28263 218 24614 D57 R L H V E L P D N Y P Y K S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.3 N.A. 77.5 N.A. 32.2 31.6 N.A. 48.5 N.A. N.A. 98.3 N.A. 28.4 83.9 30.7 79.2
Protein Similarity: 100 64.4 N.A. 77.5 N.A. 51.3 51.3 N.A. 49 N.A. N.A. 98.9 N.A. 45.9 91.9 53.6 90.7
P-Site Identity: 100 100 N.A. 0 N.A. 0 0 N.A. 100 N.A. N.A. 100 N.A. 6.6 86.6 46.6 86.6
P-Site Similarity: 100 100 N.A. 0 N.A. 13.3 13.3 N.A. 100 N.A. N.A. 100 N.A. 20 100 66.6 93.3
Percent
Protein Identity: 56.9 N.A. N.A. 52.9 49 N.A.
Protein Similarity: 74.1 N.A. N.A. 73.5 63.3 N.A.
P-Site Identity: 20 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 40 N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 15 0 8 0 0 0 8 15 0 0 % D
% Glu: 0 8 0 0 15 8 8 0 8 0 50 22 0 0 8 % E
% Phe: 0 43 8 0 0 0 15 0 0 8 0 0 0 0 8 % F
% Gly: 0 8 0 50 0 0 50 8 0 8 8 43 50 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 15 8 0 0 0 8 0 0 0 0 8 0 8 8 % I
% Lys: 50 0 0 15 0 8 0 15 0 0 8 0 8 8 0 % K
% Leu: 0 8 15 8 0 8 0 0 8 15 0 0 0 0 0 % L
% Met: 0 0 0 15 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 50 0 8 0 43 0 8 0 8 15 29 % P
% Gln: 0 0 0 0 0 36 8 0 0 0 22 0 0 0 0 % Q
% Arg: 29 15 0 0 15 8 0 8 15 0 0 0 0 0 0 % R
% Ser: 8 0 8 0 0 8 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 8 0 50 0 0 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 0 8 0 0 8 0 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 43 % W
% Tyr: 0 0 43 0 8 0 0 8 0 50 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _