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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAE
All Species:
30.61
Human Site:
T91
Identified Species:
61.21
UniProt:
P62258
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62258
NP_006752.1
255
29174
T91
E
Y
R
Q
M
V
E
T
E
L
K
L
I
C
C
Chimpanzee
Pan troglodytes
XP_001154015
256
29338
T91
E
Y
R
Q
M
V
E
T
E
L
K
L
I
C
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537764
240
27401
T91
E
Y
R
Q
M
V
E
T
E
L
K
L
I
C
C
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_113791
255
29103
T91
E
Y
R
Q
M
V
E
T
E
L
K
L
I
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518912
377
41265
T213
E
Y
R
Q
M
V
E
T
E
L
K
L
I
C
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080705
255
29168
T91
E
Y
R
Q
M
V
E
T
E
L
K
S
I
C
N
Zebra Danio
Brachydanio rerio
NP_997770
255
29054
N91
E
Y
R
Q
T
V
E
N
E
L
K
S
I
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92177
262
29780
K91
T
Y
R
G
Q
V
E
K
E
L
R
D
I
C
S
Honey Bee
Apis mellifera
XP_392479
256
29092
K91
Q
Y
R
S
Q
V
E
K
E
L
K
D
I
C
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49106
261
29644
T97
D
Y
R
G
K
I
E
T
E
L
T
K
I
C
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42644
255
28588
S93
D
Y
R
G
K
I
E
S
E
L
S
K
I
C
D
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
T93
S
Y
R
S
K
I
E
T
E
L
T
K
I
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
N.A.
93.7
N.A.
N.A.
98.8
N.A.
65.2
N.A.
96.4
96.4
N.A.
82.4
87.5
N.A.
N.A.
Protein Similarity:
100
99.2
N.A.
94.1
N.A.
N.A.
98.8
N.A.
66.5
N.A.
98.8
97.6
N.A.
90.4
92.1
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
86.6
73.3
N.A.
53.3
60
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
86.6
73.3
N.A.
60
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
71.6
N.A.
74.9
69.2
N.A.
Protein Similarity:
N.A.
82.7
N.A.
84.3
79.1
N.A.
P-Site Identity:
N.A.
53.3
N.A.
46.6
46.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
42
% C
% Asp:
17
0
0
0
0
0
0
0
0
0
0
17
0
0
25
% D
% Glu:
59
0
0
0
0
0
100
0
100
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
25
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
0
0
25
0
0
17
0
0
67
25
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
100
0
42
0
0
0
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
59
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
0
0
17
0
0
0
9
0
0
9
17
0
9
9
% S
% Thr:
9
0
0
0
9
0
0
67
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _