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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNRPE All Species: 29.39
Human Site: S70 Identified Species: 49.74
UniProt: P62304 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62304 NP_003085.1 92 10804 S70 E I H S K T K S R K Q L G R I
Chimpanzee Pan troglodytes XP_520443 92 10688 S70 E I H S K T K S R K Q L G R I
Rhesus Macaque Macaca mulatta XP_001099502 93 10762 S71 E I H S K T K S R K Q L G R I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P62305 92 10785 S70 E I H S K T K S R K Q L G R I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513314 92 10771 S70 E I H S K T K S R K Q L G R V
Chicken Gallus gallus
Frog Xenopus laevis NP_001085570 92 10841 S70 E I H L K T K S R K Q L G R I
Zebra Danio Brachydanio rerio Q7ZUG0 92 10770 N70 E V H M K T K N R K P L G R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLV5 94 11077 Q69 E V Y V K T R Q R R N L G R I
Honey Bee Apis mellifera XP_001119876 94 11010 N69 E Y H L K T K N R K P L G R I
Nematode Worm Caenorhab. elegans Q9XTU6 90 10592 G66 E V N M K T K G R N K I G R I
Sea Urchin Strong. purpuratus XP_779936 99 11476 T68 E Y H K K N K T R K P L G R I
Poplar Tree Populus trichocarpa XP_002331664 88 10309 S66 E V N I K K K S R K S L G R I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82221 80 8821 M59 N D K T D I G M V V I R G N S
Baker's Yeast Sacchar. cerevisiae Q12330 94 10357 D66 E I P V N S A D G K E D V E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 89.2 N.A. N.A. 100 N.A. N.A. 98.9 N.A. 95.6 94.5 N.A. 73.4 77.6 61.9 72.7
Protein Similarity: 100 98.9 91.4 N.A. N.A. 100 N.A. N.A. 100 N.A. 97.8 96.7 N.A. 89.3 89.3 80.4 84.8
P-Site Identity: 100 100 100 N.A. N.A. 100 N.A. N.A. 93.3 N.A. 93.3 73.3 N.A. 53.3 73.3 53.3 66.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 N.A. N.A. 100 N.A. 93.3 86.6 N.A. 80 80 80 73.3
Percent
Protein Identity: 65.2 N.A. N.A. 30.4 47.8 N.A.
Protein Similarity: 82.6 N.A. N.A. 60.8 72.3 N.A.
P-Site Identity: 66.6 N.A. N.A. 6.6 20 N.A.
P-Site Similarity: 80 N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 8 0 0 0 8 0 0 0 % D
% Glu: 93 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 8 8 0 0 0 93 0 0 % G
% His: 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 50 0 8 0 8 0 0 0 0 8 8 0 0 79 % I
% Lys: 0 0 8 8 86 8 79 0 0 79 8 0 0 0 8 % K
% Leu: 0 0 0 15 0 0 0 0 0 0 0 79 0 0 0 % L
% Met: 0 0 0 15 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 15 0 8 8 0 15 0 8 8 0 0 8 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 22 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 43 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 86 8 0 8 0 86 0 % R
% Ser: 0 0 0 36 0 8 0 50 0 0 8 0 0 0 8 % S
% Thr: 0 0 0 8 0 72 0 8 0 0 0 0 0 0 0 % T
% Val: 0 29 0 15 0 0 0 0 8 8 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _